烧伤患者血浆NT-proBNP和预后的关系分析

目的探讨烧伤患者血浆N-末端脑利钠肽(NT-proBNP)的变化对患者预后的评估价值。方法对39例严重热烧伤患者的临床资料进行回顾性分析。其中男33例,女6例;烧伤面积30%⁹8%体表面积,平均(65.5%±23.68%);年龄1998%体表面积,平均(65.5%±23.68%);年龄19⁷2岁,平均(36.8±16.8)岁。观察39名患者心力衰竭情况、血浆NT-proBNP、肌钙蛋白I(cTnT)、心功能和患者的预后情况。结果 9例出现心力衰竭的烧伤患者NT-proBNP是(1 676.03±2 190.41)pg/L,其中3例患者死亡。30例没有出现心力衰竭的烧伤患者NT-proBNP是(196.97±104.39)pg/L,其中1例患者死亡。心衰组与无心衰组两组死亡率差异有显著性意义(p<0.01)。结论严重烧伤患者合并出现心力衰竭死亡率高,NT-proBNP能很好地评估严重烧伤患者的预后。

ANALYSIS OF THE RELATIONSHIP BETWEEN THE PLASMA NT -proBNP AND PROG-NOSIS IN BURN PATIENTS

Objective Severe burns often complicated with myocardial injury and heart failure.In order to investi-gate the burn patients plasma N-terminal pro brain natriuretic peptide （ NT-proBNP） assessment of the changes on prognosis of the patients.Methods The clinical data of 39 cases of severe burn patients were retrospectively analyzed.Including 33 males and 6 females.Burn area of 30%～98% of body surface area, average（65.5%±23.68%）, age 19 to 72 years, av-erage （36.8 ±16.8） years old.Observation of 39 patients with heart failure, plasma NT-proBNP, cardiac troponin I （cT-nT） , cardiac function and prognosis in patients with.Results 9 cases of heart failure patients with burn NT -proBNP is （1 676.03 ±2 190.41） pg/L, of which 3 patients died.30 cases of burn patients without heart failure NT -proBNP is （196.97 ±104.39）pg/L, of which 1 patients died.Heart failure group and without heart failure group two groups mortality was significantly difference （p〈0.01）.Conclusion severe burn patients with heart failure with high mortality, NT-proB-NP can well evaluate the prognosis of patients with severe burn.