短暂性脑缺血发作患者颅内外动脉狭窄的分布与预后的相关临床分析

目的观察短暂性脑缺血发作（TIA）患者颅内外动脉狭窄的分布情况，评价颅内外动脉狭窄的分布与预后的关系。方法对121例TIA患者行经颅多普勒（，TCD），颈动脉彩超和头颈部磁共振血管成像（MRA）检查，统计颅内外动脉狭窄的分布，随访1年，观察卒中的再发率。结果121例患者中，单纯颅内动脉、单纯颅外动脉及颅内外动脉混合狭窄分别为52．1％（63／121）、15．90%（16／121）、25．6％（31／121），颅内动脉狭窄高于颅外动脉（75．7％、24．3％）。最常见的受累部位为大脑中动脉和颈内动脉颅内段。随访1年后，颅内外动脉混合狭窄者卒中再发率高于单纯颅内、外动脉狭窄者。结论TIA患者以颅内动脉狭窄多见，不同颅内外动脉狭窄的分布可能是TIA患者卒中复发的血管性预测因子。

Correlation between distribution of intracranial or extracranial arteriostenosis and prognosis in patients with transient ischemic attack

Objective To investigate the distribution of intracranial or extracranial arteriostenosis in patients with transient ischemic attack （TIA）, and analyze the correlation between distribution of arteriostenosis and prognosis.Methods 121 patients of TIA were detected with transcranial color doppler （TCD）, carotid doppler and magetic resonance angiography （MRA）. Calculate the freqnency of stenesis of the intracranial and extracranial arteries. Results 15.9% （16/121）of the cases had either extracranial arteriostenosis. 52.1% （63/121） of the cases had either intracranial arteriostenesis. 25.6% （31/121 ） of the cases had multiple intracranial and extracranial arteriostenosis. In general, there were more patients with intracmnial artefiostcnosis than extracranial arteriostenosis （75.7%vs 24.3% ）,and middle cerebral artery（MCA） and intracranial carotid artery（I-ICA）are affected frequently.In follow - up cases,the stroke incidence of multiple intracranial and extracranial arteriostenosis was higher than that of either intracranial or extracranial arteriostenosis in one year. Conclusion Intracmnial arteriostenosis is more fi-equently encountered in those with TIA. The distribution of intraeranial or extracranial artefiostenosis may be a predictor of recurrence of stroke.