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Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus
Authors:Parul H. Kothari  Weiliang Qiu  Damien C. Croteau-Chonka  Fernando D. Martinez  Andrew H. Liu  Robert F. Lemanske  Carole Ober  Jerry A. Krishnan  Dan L. Nicolae  Kathleen C. Barnes  Stephanie J. London  Albino Barraza-Villarreal  Steven R. White  Edward T. Naureckas  Joshua Millstein  W. James Gauderman  Frank D. Gilliland  Vincent J. Carey  Benjamin A. Raby
Affiliation:1. Channing Division of Network Medicine, Department of Medicine, Brigham and Women''s Hospital and Harvard Medical School, Boston, Mass;2. Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women''s Hospital and Harvard Medical School, Boston, Mass;p. Pulmonary Genetics Center and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women''s Hospital and Harvard Medical School, Boston, Mass;3. Asthma and Airway Disease Research Center, University of Arizona Health Sciences, Tucson, Ariz;4. Section of Pulmonary Medicine, Department of Pediatrics, Children''s Hospital Colorado, National Jewish Health and University of Colorado School of Medicine, Denver, Colo;5. University of Wisconsin School of Medicine and Public Health, Madison, Wis;6. Department of Human Genetics, University of Chicago, Chicago, Ill;8. Departments of Medicine and Statistics, University of Chicago, Chicago, Ill;12. Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Ill;7. Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Ill;9. Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado, the Anschutz Medical Campus, Aurora, Colo;10. Division of Intramural Research, Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC;11. National Institute of Public Health, Cuernavaca, Morelos, Mexico;13. Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, Calif;14. Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, Calif;15. Partners HealthCare Personalized Medicine, Partners Health Care, Boston, Mass
Abstract:
Keywords:on behalf of the
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