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Propagation of respiratory viruses in human airway epithelia reveals persistent virus-specific signatures
Authors:Manel Essaidi-Laziosi  Francisco Brito  Sacha Benaoudia  Léna Royston  Valeria Cagno  Mélanie Fernandes-Rocha  Isabelle Piuz  Evgeny Zdobnov  Song Huang  Samuel Constant  Marc-Olivier Boldi  Laurent Kaiser  Caroline Tapparel
Affiliation:1. Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva, Switzerland;2. Swiss Institute of Bioinformatics, University of Geneva Medical School, Geneva, Switzerland;3. Epithelix Sàrl, Geneva, Switzerland;4. Division of Medical Specialties and Laboratory of Virology, University Hospital of Geneva, Geneva, Switzerland;5. Research Center for Statistics, Faculty GSEM, University of Geneva, Geneva, Switzerland
Abstract:
Keywords:Respiratory virus  rhinovirus  cytotoxicity  pathogenesis  cytokines  mucociliary clearance  immune response  persistence  dpi  Days after infection  EV  Enterovirus  HCoV  Human coronavirus  HTS  High-throughput RNA sequencing  IP-10  Interferon-inducible protein 10  LDH  Lactate dehydrogenase  MCC  Mucociliary clearance  qPCR  Real-time quantitative PCR  RSV  Respiratory syncytial virus  RV  Rhinovirus  TEER  Transepithelial electrical resistance
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