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Single-cell profiling of peanut-responsive T cells in patients with peanut allergy reveals heterogeneous effector TH2 subsets |
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| Authors: | David Chiang Xintong Chen Stacie M. Jones Robert A. Wood Scott H. Sicherer A. Wesley Burks Donald Y.M. Leung Charuta Agashe Alexander Grishin Peter Dawson Wendy F. Davidson Leah Newman Robert Sebra Miriam Merad Hugh A. Sampson Bojan Losic M. Cecilia Berin |
| Affiliation: | 1. Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY;2. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY;9. Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY;3. Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children''s Hospital, Little Rock, Ark;4. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Md;5. Department of Pediatrics, University of North Carolina, Chapel Hill, NC;6. Department of Pediatrics, National Jewish Health, Denver, Colo;7. EMMES Corporation, Rockville, Md;8. National Institutes of Health (National Institute of Allergy and Infectious Diseases), Bethesda, Md |
| Abstract: |  |
| Keywords: | Food allergy peanut allergy regulatory T tolerance CoFAR Consortium of Food Allergy Research CRTH2 CSF2 Colony-stimulating factor 2 DEG Differentially expressed gene FoxP3 Forkhead box P3 HC Healthy control HT High threshold MSSM Mount Sinai School of Medicine PA Peanut allergy RNA-seq RNA sequencing TCR T-cell receptor Treg Regulatory T |
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