成人正常肾脏体素内不相干运动扩散加权成像

目的：定量分析成人正常肾脏体素内不相干运动扩散加权成像(IVIM-DWI)参数特征,评估不同部位、性别和年龄对IVIM-DWI 参数的影响。方法招募30例健康成人志愿者行肾脏 IVIM-DWI 检查,2名影像医师分别测量双肾上极、中部和下极肾实质的 D 值、D?值和 f 值。结果成人正常肾脏中部的 D 值、D?值和 f 值分别为(1.61±0.16)×10-3 mm2/s、(17.45±3.78)×10-3 mm2/s和(26.88±5.19)%。右肾的 D 值高于左肾(P <0.05)。男性志愿者肾脏的 f 值高于女性(t=3.321,P =0.001)。正常肾脏>50岁组的 D 值低于≤50岁组(t=3.548,P =0.001),年龄和 D 值呈负相关(r =-0.406)。2位观察者测量的 D 值、D?值和 f 值的组内相关系数分别为0.881,0.56和0.741,肾脏中部 IVIM-DWI 各参数的一致性高于肾脏上极和下极。结论成人正常肾脏 IVIM-DWI 参数受不同部位、性别和年龄的影响。

Intravoxel incoherent motion diffusion weighted imaging of normal adult kidney

Objective To analyze quantitatively intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI)of normal adult kidney and to evaluate the effects of the location of the kidney,gender and age on IVIM-DWI parameters.Methods Thirty healthy adult volunteers were recruited to undergo IVIM-DWI examination.Two radiologists measured the D ,D? and f values of renal parenchyma in both the upper pole,middle part and lower pole of the kidneys separately.Results The D ,D? and f values of the middle part of kidneys in healthy adult were(1.61±0.1 6)×10 -3 mm2/s,(1 7.45 ±3.78)×10 -3 mm2/s and (26.88 ±5.1 9)%, respectively.The D values of right kidney were higher than that of left kidney (P <0.05).The f values of normal kidney in male volunteers were higher than that of female (t = 3.321,P =0.001).The D values of normal kidney in > 50 years group were lower than that of ≤50 years group (t = 3.548,P=0.001).D value of the kidney and age was negatively correlated (r=-0.406).Intraclass correlation coefficient of D,D? and f values between two observers were 0.881,0.56 and 0.741,respectively.The consistency of two observers in measurement of IVIM-DWI parameters in the middle part of kidneys was higher than that of the upper pole and lower pole of the kidneys.Conclusion The IVIM-DWI parameters of adult normal kidneys are influenced by different parts of the kidney,gender and age.