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| 远端组织缺血预处理对心脑保护作用的研究进展 | |
| 引用本文： | 翁立军,张野. 远端组织缺血预处理对心脑保护作用的研究进展[J]. 国际麻醉学与复苏杂志, 2009, 31(5): 254-257. DOI: 10.3760/cma.j.issn.1673-4378.2010.03.018 |
| 作者姓名： | 翁立军 张野 |
| 作者单位： | 安徽医科大学第二附属医院麻醉科,合肥,230601; |
| 摘 要： | 缺血/冉灌注(ischemia reperfusion,I/R)损伤可导致局部和/或远端组织器官的损伤;缺血预处理(ischemic preconditioning,IPC)是对I/R损伤的一种有效处理方式;远端预处理(remote preconditioning,RPC)是继IPC后一种新兴的,更简单又经济的,高效的保护组织器官免受缺血损伤的策略,其机制涉及神经和/或体液两大因素的调节作用,在临床上已有试用. |
| 关 键 词： | 远端预处理 机制 临床应用 |
Advance in protective effects of remote ischemic preconditioning on heart and brain |
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| WENG Li-jun,ZHANG Ye. Advance in protective effects of remote ischemic preconditioning on heart and brain[J]. international journal of anesthesiology and resuscitation, 2009, 31(5): 254-257. DOI: 10.3760/cma.j.issn.1673-4378.2010.03.018 | |
| Authors: | WENG Li-jun ZHANG Ye |
| Abstract: | Ischemia/reperfusion injury (I/R) results in local and/or remote organ injury. Ischemic preconditioning (IPC) has been shown to protect organs against I/R. Remote ischemic preconditioning (RPC) is a new, easy and convenient strategy to protect organs against I/R by inducing a prior brief period (s) of I/R to an organ remote from that undergoing sustained injury. The mechanisms may involve in regulation of humoral and/or neural factors and this strategy has been applied in clinical trials. |
| Keywords: | Remote preconditioningMechanismClinical application |