首页 | 本学科首页   官方微博 | 高级检索  
     


Assimilatory and excretory function of the isolated perfused dog liver
Authors:R. L. Rozental'  G. I. Tsimermane  D. B. Krivulis  A. A. Sondore  Yu. A. Sorokin
Abstract:
In experiments on dogs the assimilatory-excretory function of the liver was studied by means of the bromsulfthalein method in the intact animal and during perfusion of the isolated organ through the portal vein by means of an artificial circulation apparatus. Under perfusion conditions the rate of uptake of the dye was 50–60% of the value of this index in the intact animal. The rate of elimination of bromsulfthalein with the bile and the biliary plasma clearance in the intact animal were five to six times higher. The main cause of the reduction in the assimilatory-excretory function of the isolated liver is evidently hypoxia developing after denervation and removal of the organ from the body, and also during extracorporeal perfusion itself.Laboratory of Experimental Surgery, Medical Institute, Riga. (Presented by Academician of the Academy of Medical Sciences of the USSR N. N. Savitskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 4, pp. 405–407, April, 1976.
Keywords:liver  liver functions  bromsulfthalein method  perfusion
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号