Detection of caspofungin resistance in Candida spp. by Etest |
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Authors: | Desnos-Ollivier Marie Dromer Françoise Dannaoui Eric |
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Affiliation: | Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA3012, Institut Pasteur, Paris Cedex 15, France. |
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Abstract: | The caspofungin susceptibilities of 28 Candida sp. clinical isolates, including 8 caspofungin-resistant isolates characterized by mutations in the Fks1 protein, were determined by the Etest in RPMI and AM3 media. Good discrimination between wild-type and mutant isolates was obtained. These results suggest that the Etest is valuable for the detection of caspofungin resistance in Candida spp. |
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