| 人中性粒细胞防御素的研究进展 |
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| 引用本文： | 朱国华,齐名,黄宇烽. 人中性粒细胞防御素的研究进展[J]. 医学研究生学报, 2004, 17(12): 1131-1134 |
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| 作者姓名： | 朱国华 齐名 黄宇烽 |
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| 作者单位： | 南京军区南京总医院解放军医学检验中心,江苏南京,210002 |
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| 摘 要： | 人中性粒细胞防御素是机体天然防御体系的重要组成部分，存在于人中性粒细胞中，具有广泛的杀菌活性、细胞毒性及趋化作用，是当前国内、外生物医学研究的热点。作者对人中性粒细胞防御素的分子生物学特征、生物学活性研究进展及其病理生理作用作一综述。
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| 关 键 词： | 防御素 中性粒细胞 天然免疫 |
| 文章编号： | 1008-8199(2004)12-1131-04 |
| 修稿时间： | 2004-04-15 |
Recent progress in research on human neutrophil peptides |
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| ZHU Guo-hua reviewing,QI Ming,HUANG Yu-feng checking. Recent progress in research on human neutrophil peptides[J]. Bulletin of Medical Postgraduate, 2004, 17(12): 1131-1134 |
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| Authors: | ZHU Guo-hua reviewing QI Ming HUANG Yu-feng checking |
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| Abstract: | Human neutrophils defensins, e.g., human neutrophils peptides (HNP), had been found in polymorphonuclear neutrophil and shown broad antimicrobial activity, cytotoxicity and chemotaxis as an important family of human innate defence components. The researches on defensins is becoming a worldwide major focus of biological and medical attention nowadays. The researches on molecular characteristics, biological and pathophysiological activities of HNP are reviewed. |
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| Keywords: | Defensin Neutrophil Innate immunity |
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