Restriction mapping of genome and nucleotide sequence of Aujeszky's disease virus strains isolated in CIS

Auesku disease virus--suid herpesvirus type I (SHV-1) genome is analyzed by the restriction fragment pattern analysis. The analyzed strains isolated in CIS countries in 1962-1992 were compared with the European strains. Genomes of field strains Arsk, Turkmenia, and Geneva differed and even lacked the restriction fragments typical of vaccine strains MK-25 or UNIIEV-18S, which agrees with the results of the neutralization test. Immunobiological characteristics of SHV-1 strains are discussed.