AECOPD合并低钠血症临床研究

目的 探讨AECOPD合并低钠血症患者的临床特点和治疗方法.方法 观察组56例,随机抽取同期诊断为AECOPD且血钠正常的患者56例为对照组,对两组资料进行对比分析.结果 观察组与对照组相比,病程较长,吸烟指数大,出汗多,心律失常发生率高,呼吸频率增快,意识障碍患者数量多且病情重,COPD分级重度及极重度多,血钾及血氯降低,血气分析pH值、动脉血氧分压及动脉血氧饱和度降低,动脉血二氧化碳分压上升,住院天数延长,好转率下降,死亡率上升,均有统计学意义（P＜0.01,P＜0.05）.结论 临床上应予高度重视,提高对低钠血症的认识,做到早期发现、早期诊断、早期治疗,以提高治愈好转率,降低病死率.

Clinical study on patients with acute exacerbations of chronic obstructive pulmonary disease complicated with hyponatremia

Objective To discuss the clinical features and treatment of patients with AECOPD complicated with hyponatremia. Methods 56 AECOPD patients complicated with hyponatremia were taken as the observation group, and another 56 AECOPD patients with normal serum sodium were selected as the control group. Their clinical data were compared and analyzed. Results Compared with the control group, the observation group had longer course of disease, larger smoking index, more sweat, higher incidence of arrhythmia, faster respiratory rate, more patients with severe disorders of consciousness, more severe degrees of COPD, lower blood potassium and chloride, lower blood gas analysis of pH, arterial oxygen pressure and arterial oxygen saturation, higher arterial carbon dioxide partial pres- sure, longer hospital stay, lower improvement rate, and higher mortality （ P 〈 O. O1, P 〈 O. 05 ）. Conclusion AECOPD patients compli- cated with hyponatremia should be paid more attention to give early diagnosis and treatment in order to improve their curative rate and lower mortality.