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| 颅颈部蛛网膜下腔改变与Chiari畸形发病机理的临床研究 | |
| 引用本文： | 陈焕然,许民辉,邹咏文,徐伦山. 颅颈部蛛网膜下腔改变与Chiari畸形发病机理的临床研究[J]. 局解手术学杂志, 2003, 12(3): 205-208 |
| 作者姓名： | 陈焕然 许民辉 邹咏文 徐伦山 |
| 作者单位： | 陈焕然（第三军医大学附属大坪医院野战外科研究所,重庆,400042） 许民辉（第三军医大学附属大坪医院野战外科研究所,重庆,400042） 邹咏文（第三军医大学附属大坪医院野战外科研究所,重庆,400042） 徐伦山（第三军医大学附属大坪医院野战外科研究所,重庆,400042） |
| 摘 要： | 目的 研究Chiari畸形I型(CMI)患者颅颈部蛛网膜下腔(SS)形态学改变及其在疾病发生中的意义。方法 测定病例组和正常对照组颅颈部蛛网膜下腔形态学指标，进行对比分析；在术中观察病例组颅颈部不同组织变异情况。结果 此类患者由于先天性和后天性因素，使整个颅颈部蛛网膜下腔进行性狭窄，其中以枕大池的缩窄最为明显，颈延髓前池和侧池亦有不同程度的缩小，与对照组差异显著。结论 颅颈部蛛网膜下腔进行性狭窄可能在疾病发生发展中起重要作用。 |
| 关 键 词： | 颅颈部 蛛网膜下腔 Chiari畸形 发病机理 临床研究 形态学 进行性狭窄 脊髓空洞 |
| 文章编号： | 1672-5042(2003)03-0205-04 |
| 修稿时间： | 2003-07-13 |
Alteration of subarachnoid space in the craniocervical junction and its clinical significance in the pathogenesis of Chiari malformation |
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| CHEN Huan-ran,XU Ming-hui,ZHOU Yong-wen,et al.. Alteration of subarachnoid space in the craniocervical junction and its clinical significance in the pathogenesis of Chiari malformation[J]. Journal of Regional Anatomy and Operative Surgery, 2003, 12(3): 205-208 | |
| Authors: | CHEN Huan-ran XU Ming-hui ZHOU Yong-wen et al. |
| Affiliation: | CHEN Huan-ran,XU Ming-hui,ZHOU Yong-wen,et al. Research Institute of Surgen,Third Military Medical University,Chongqing 400042,China |
| Abstract: | Objective To investigate the alteration of subarachnoid space (SS) in the craniocervical junction (CCJ) region of the patientswith type I Chiari malformation (CMI), and to study its clinical significance in the pathogenesis. Methods We reviewed the clinical manifestations and the magnetic resonance image (MRI) information of 34 CMI patients, with 20 normal people as control group. Results Findings in the CMI patients consisted of the narrows of subarachnoid space at the CCJ region, which were aggravated gradually by innate and postnatal factors. Conclusion The narrow of subarachnoid space can cause cerebrospinal fluid circulation disorder at the CCJ region, which plays an important role in the occurrence and development of the disease. |
| Keywords: | type I Chiari malformations subarachnoid space pathogenesis |
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