Abstract: | Timely and important studies are reviewed and commentaries provided by leading palliative care. Symptoms addressed in this issue are opioid resistant pain, itching, osteonecrosis, sever acute pain, insomnia, fatigue, and fever. Studies addressing the use of opioid rotation to manage opioid resistant pain, lidocaine for priritus due to cholestatic liver disease, osteonecrosis following use of bisphosphonates, morphine dosing for severe acute pain, sedative-hypnotics for older patients, central stimulants for chronic fatigue, and use of alternating ibuprofen and acetaminophen as an antipyretic regimen are presented. |