| 过敏性鼻炎患者总IgE、嗜酸性粒细胞和特异性IgE结果分析 |
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| 引用本文： | 王佶图,王学艳,刘娜,张曼. 过敏性鼻炎患者总IgE、嗜酸性粒细胞和特异性IgE结果分析[J]. 标记免疫分析与临床, 2019, 26(8): 1265-1268 |
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| 作者姓名： | 王佶图 王学艳 刘娜 张曼 |
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| 作者单位： | 首都医科大学附属北京世纪坛医院医学检验科,北京大学第九临床医学院医学检验科,尿液细胞分子诊断北京市重点实验室,北京100038;首都医科大学附属北京世纪坛医院变态反应科,北京,100038 |
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| 基金项目： | 北京市医管局首届登峰人才计划;尿液细胞分子诊断北京市实验室建设经费 |
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| 摘 要： | 目的 探讨血清总IgE(immunoglobulin E,IgE)水平及外周血嗜酸性粒细胞(eosinophil,EOS)计数在过敏性鼻炎(allergic rhinitis,AR)诊断中的作用,以及两者与血清特异性IgE(specific immunoglobulin E,sIgE)水平之间的关系。方法选择对蒿属花粉过敏的过敏性鼻炎患者60例作为鼻炎组,60例健康人作为对照组。将鼻炎组分为男性组与女性组,青年组(18~40岁)与中年组(41~65岁),将鼻炎组患者根据sIgE结果分为:中低水平(0.35 IU/mL≤sIgE<3.5IU/mL)、高水平(3.5 IU/mL≤sIgE<17.5 IU/mL)与极高水平(sIgE≥17.5 IU/mL)。结果 鼻炎组总IgE水平和EOS计数均高于对照组,差异有统计学意义( P <0.05);鼻炎组、男性组、女性组、青年组和中年组总IgE与sIgE均成正相关( r s =0.541,0.490,0.599,0.566,0.462,均 P <0.05);鼻炎组患者总IgE与sIgE等级成正相关( rs =0.449, P <0.05)。结论 血清总IgE可作为AR诊断辅助指标,联合检测血清总IgE及sIgE可为AR的诊断提供更充分的依据。
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| 关 键 词： | 过敏性鼻炎 特异性IgE 嗜酸性粒细胞 总IgE |
The Detection Results of Total IgE,Eosinophil and Specific IgE in Patients with Allergic Rhinitis |
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| WANG Ji-tu,WANG Xue-yan,LIU Na,ZHANG Man. The Detection Results of Total IgE,Eosinophil and Specific IgE in Patients with Allergic Rhinitis[J]. Labeled Immunoassays and Clinical Medicine, 2019, 26(8): 1265-1268 |
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| Authors: | WANG Ji-tu WANG Xue-yan LIU Na ZHANG Man |
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| Affiliation: | (Department of Clinical Laboratory,Beijing Shijitan Hospital,Capital Medical University,Department of Clinical Laboratory,Peking University Ninth School of Clinical Medicine,Beijing Key Laboratory of Urinary Cellular and Molecular Diagnostics,Beijing 100038,China;Department of Allergy,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China) |
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| Abstract: | WANG Ji-tu;WANG Xue-yan;LIU Na;ZHANG Man(Department of Clinical Laboratory,Beijing Shijitan Hospital,Capital Medical University,Department of Clinical Laboratory,Peking University Ninth School of Clinical Medicine,Beijing Key Laboratory of Urinary Cellular and Molecular Diagnostics,Beijing 100038,China;Department of Allergy,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China) |
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| Keywords: | Allergic rhinitis Specific IgE Eosinophil Total IgE |
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