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The prevalence and impact of falls in elderly dialysis patients: Frail elderly Patient Outcomes on Dialysis (FEPOD) study
Institution:1. Department of Nephrology and Hypertension, University Medical Center Utrecht, Heidelberglaan 100, the Netherlands;2. Department of Internal Medicine, Division of Medicine for the Elderly, Maastricht University Medical Center, Maastricht, the Netherlands;3. John Walls Renal unit, Leicester General Hospital, Leicester, United Kingdom;4. Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom;5. Departments Geriatrics, Diakonessenhuis Utrecht, the Netherlands;1. Department of Rehabilitation, Kitasato University Hospital, Sagamihara, Japan;2. Department of Healthcare Epidemiology, School of Public Health in the Graduate School of Medicine, Kyoto University, Kyoto, Japan;3. Department of Medicine, Division of Nephrology, University of California Davis, Sacramento, California;4. Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan;5. Division of Nephrology, Toho University Ohashi Medical Center, Tokyo, Japan;7. Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, Isehara, Japan;1. Division of Nephrology and Hypertension, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California;2. Division of Nephrology, Tianjin Union Medical Center, Tianjin, People’s Republic of China;3. Division of Nephrology, CHA Gumi Medical Center, CHA University, Daegu, South Korea;4. Department of Nephrology, the First Affiliated Hospital of Xiamen University, People’s Republic of China;5. Rehabilitation Clinical Trials Center, Division of Respiratory and Critical Care Physiology and Medicine Los Angeles Biomedical Research Institute at Harbor- University of California–Los Angeles Medical Center, Torrance, California;7. University of California–Los Angeles Clinical and Translational Science Institute, Los Angeles Biomedical Research Institute at Harbor–University of California–Los Angeles Medical Center, Torrance, California;11. Harold Simmons Center for Kidney Disease Research and Epidemiology, Los Angeles Biomedical Research Institute at Harbor–University of California–Los Angeles Medical Center, Torrance, California;12. Division of Psychology, Department of Psychiatry, Harbor–University of California–Los Angeles Medical Center, Torrance, California;8. Division of Nephrology and Hypertension, University of California at Irvine, Orange, California;9. University of California Los Angeles Fielding School of Public Health, Los Angeles, California;71. David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California;112. VA Boston Health Care system/Harvard South Shore Psychiatry Residency Program, Brockton, Massachusetts;1. Nutrition Institute, Rio de Janeiro State University, Rio de Janeiro, Brazil;2. Nutrition Graduation Program and Nephrology Division, Federal University of São Paulo, São Paulo, Brazil;1. Department of Public Health, Epidemiology, and Health Economics, University of Liège, Liège, Belgium;2. Department of Sport and Rehabilitation Sciences, University of Liège, Liège, Belgium;3. Department of Geriatrics, University Teaching Hospital (CHU), Liège, Belgium;1. Department of Rehabilitation Sciences, Prince Sattam Bin Abdulaziz University, Saudi Arabia;2. Department of Physical Therapy and Rehabilitation Sciences, Jazan University, Saudi Arabia;3. Department of Educational Psychology, University of Kansas, United States;1. School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;2. School of Management, Harbin Institute of Technology, Harbin, China
Abstract:BackgroundAs the numbers of older patients on dialysis rise, geriatric problems such as falling become more prevalent. We aimed to assess the prevalence of falls and the impact on mortality and quality of life in frail elderly patients on assisted PD (aPD) and hemodialysis (HD) from the FEPOD Study.MethodsData on falls and quality of life were collected with questionnaires at baseline and every six months during 2-year follow-up. Multiple regression analysis was used to evaluate factors associated with falls. Additionally, we performed a review of literature concerning the relation between falls and poor outcome.ResultsBaseline fall data were available for 203 patients and follow-up data for 114 patients. Dialysis modality was equally distributed (49% HD and 51% aPD). Mean (SD) age was 75 ± 7 years. Fall rate was 1.00 falls/patient year, comparable in HD and aPD. Falls led to fear of falling, resulting in less activities in 68% vs 42% (p < 0.01) and leaving the house less in 59% vs 31% (p < 0.01) of patients. Patients with diabetes mellitus were twice as likely to report falls at baseline (OR 1.91 95%CI 1.00–3.63], p = 0.05) and falls at baseline were associated with falls during follow-up (OR 2.53 95%CI 1.06–6.04] p = 0.03). Literature revealed frailty was a strong risk factor for falling and falling results in a higher mortality and hospitalization rate.ConclusionFalls were frequent in older dialysis patients and have a negative impact on quality of life. Fall incidence is comparable between aPD and HD.
Keywords:Dialysis  Falls  Quality of life  Fractures
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