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前列腺素E1治疗糖尿病肢端坏疽疗效观察
引用本文:宋瑞捧 袁群. 前列腺素E1治疗糖尿病肢端坏疽疗效观察[J]. 中原医刊, 2006, 33(10): 16-17
作者姓名:宋瑞捧 袁群
作者单位:河南省地质医院,北京空军总医院内分泌科 郑州450006
摘    要:目的探讨前列腺素E1对糖尿病肢端坏疽的治疗效果。方法自2004年6月~2006年2月对58例患者,采取随机分组,治疗组30例用前列腺素E1加基础治疗方法,对照组28例用复方丹参加基础治疗,观察84 d。结果治疗组溃疡总有效率90%,疼痛总有效率83%,观察组溃疡总有效率60%,疼痛总有效率57%,治疗前后两组患者的股动脉、腘动脉及足背动脉内径和血流量差异均有统计学意义(P<0.05)。结论前列腺素E1是治疗糖尿病肢端坏疽的有效药物。

关 键 词:前列腺素E1  糖尿病肢端坏疽
收稿时间:2006-02-24
修稿时间:2006-02-24

Prostaglandin Et for treating foot gangrene in diabetic patients
SONG Ruipeng, YUAN Qun. Prostaglandin Et for treating foot gangrene in diabetic patients[J]. Central Plains Medical Journal, 2006, 33(10): 16-17
Authors:SONG Ruipeng   YUAN Qun
Affiliation:1. Geological Hospital of Henan , Zhengzhou 450006, Henan ; 2. Department of Endocrinology, the General Hospital of PLA Air Force
Abstract:Objective To probe the effect of prostaglandin E_1(PGE_1)in treating diabetic foot gangrene.Methods Fifty-eight patients were selected and divided into 2 groups randomly from Jun.2004 to Feb.2006.Then the 30 patients in the experimental group were treated with prostaglandin E_1 adding basic therapy,while 28 patients in control group were treated with compound dansen for 84 days.Results In experimental group,the total curative rate of foot ulcer was 90% and the total curative rate of the pain was 83%,while in control group the total curative rate of foot ulcer was 60% and the pain was 57%.There curative were significant differences(P<0.05) in inner diameter and the blood flow in the femoral artery,popliteal artery and dorsal pedal before and after treatment in two groups.Conclusion Prostaglandin E_1 is an effective drug for treating diabetic foot gangrene.
Keywords:Prostaglandin E_1  Diabetic foot gangrene
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