|
|||||
|
|
| Establishment of an animal model of non-transthoracic cardiopulmonary bypass in rats | |
| 引用本文： | 商宏伟 肖颖彬 刘梅 陈林. Establishment of an animal model of non-transthoracic cardiopulmonary bypass in rats[J]. 中华创伤杂志(英文版), 2005, 8(5): 289-292 |
| 作者姓名： | 商宏伟 肖颖彬 刘梅 陈林 |
| 作者单位： | Department of Cardiovascular Surgery，Xinqiao Hospital，Third Military Medical University，Chongqing400037，China，Department of Cardiovascular Surgery，Xinqiao Hospital，Third Military Medical University，Chongqing400037，China，Department of Cardiovascular Surgery，Xinqiao Hospital，Third Military Medical University，Chongqing400037，China，Department of Cardiovascular Surgery，Xinqiao Hospital，Third Military Medical University，Chongqing400037，China |
| 摘 要： | Caeonvrdeairbol ptihnueglm fotuhnneacrty iso ubnrysgpe aoosfns st h(etCo PhB eo)apret tre aamtnepdo o rtnahreil ay l ut nangkosen,s-working heart.And it is an essential component ofconventional cardiac surgery.Although manyimprovements have been made to i… |
| 关 键 词： | 动物模型 非经胸廓心肺旁路手术 氧合器 动脉压力 导管插入术 |
Establishment of an animal model of non-transthoracic cardiopulmonary bypass in rats |
|
| SHANG Hong-wei,XIAO Ying-bin,LIU Mei,CHEN Lin. Establishment of an animal model of non-transthoracic cardiopulmonary bypass in rats[J]. Chinese journal of traumatology, 2005, 8(5): 289-292 | |
| Authors: | SHANG Hong-wei XIAO Ying-bin LIU Mei CHEN Lin |
| Affiliation: | Department of Cardiovascular Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China |
| Abstract: | Objective: To establish an animal model of non-transthoracic cardiopulmonary bypass (CPB) in rats. Methods: Ten adult male Sprague-Dawlay rats, weighing 350-500 g, were used in this study. CPB was established in these animals through cannulating the left carotid and right jugular vein for arterial perfusion and venous return. The components of perfusion circuit, especially the miniature oxygenator and cannula, were specially designed and improved. The mean arterial pressure was measured with a blood pressure meter through cannulating the left femoral artery. The hemodynamic and blood gas parameters were also monitored. Results: The rat model of non-transthoracic CPB was established successfully. The hemodynamical parameters were changed within an acceptable region during CPB. The miniature oxygenator was sufficient to meet the standard of satisfactory CPB. Conclusions: The rat model of non-transthoracic CPB established through the carotid and jugular cannulation is feasible, easily operated, safe, reliable, and economic. It is an ideal model for the pathophysiological research of CPB. |
| Keywords: | Blood gas analysis Hemodynamic phenomena Rats Non-transthoracic cardiopulmonary bypass |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |