|
|||||
|
|
| 先天性胆道闭锁肝内毛细胆管超微结构与临床预后关系探讨 | |
| 引用本文： | 陈洁 李桂生. 先天性胆道闭锁肝内毛细胆管超微结构与临床预后关系探讨[J]. 中华小儿外科杂志, 1999, 20(5): 294-295 |
| 作者姓名： | 陈洁 李桂生 |
| 作者单位： | [1]暨南大学医学院第一附属医院小儿外科 [2]中山医科大学第一附属医院小儿外科 |
| 摘 要： | 目的 探讨先天性胆道闭锁（ＣＢＡ）肝脏毛细胆管超微结构与临床预后的关系。方法 用ＰｈｉｌｉｐｓＣＭ１０透射电镜观察肝内毛细胆管超微结构，比较肝组织电镜切片中发育良好与发育不良的毛细胆管数目并与临床预后作比较。结果 ２７例ＣＢＡ患儿中，肝内毛细胆管发育良好为主１３例，其中１２例术后生存，生存率为９２．３１％；毛细胆管发育不良为主的１４例中，仅有４例生存，生存率为２８．５７％，两组生存率有显著性差异（ |
| 关 键 词： | 胆道闭锁 先天性 肝内 毛细胆管 超微结构 预后 |
Ultrastructure of Intrahepatic Biliary Canaliculi and Prognosis of Biliary Atresia. |
|
| CHEN Jie,LI Guisheng,LIU Juncheng,et al.. Ultrastructure of Intrahepatic Biliary Canaliculi and Prognosis of Biliary Atresia.[J]. Chinese Journal of Pediatric Surgery, 1999, 20(5): 294-295 | |
| Authors: | CHEN Jie LI Guisheng LIU Juncheng et al. |
| Affiliation: | CHEN Jie,LI Guisheng,LIU Juncheng,et al. Department of Pediatric Surgery,The First Affiliated Hospital,Medical College of Jinan University,Guangzhou 510630 |
| Abstract: | Objective To investigate the relationship between the ultrastructure of intrahepatic biliary canaliculi and the prognosis of biliary atresia. Methods Transmission electromicroscopy(Philips CM10) was performed on the liver biopsies from 27 patients who were operated on congenital biliary atresia. The number of well developed biliary canaliculi was correlated with the prognosis. Results The survival rates of 13 patients with well developed intrahepatic biliary canaliculi and 14 patients with poorly developed intra hepatic biliary canaliculi were 92.3?% (12/13) and 28.6?% (4/14) respectively. The difference between the two groups was statistically significant( P < 0.05 ). Conclusion Intra hepatic biliary canaliculi ultrastructure could be used as one of the prognostic factors in biliary atresia. |
| Keywords: | Biliary tract disease Bile canaliculi Prognosis |
| 本文献已被 CNKI 维普 等数据库收录！ | |