A preliminary study of apoptosis induction in glioma cells via alteration of the Bax/Bcl-2-p53 axis by transformed and non-transformed root extracts of Leonurus sibiricus L. |
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Authors: | Sitarek Przemysław Skała Ewa Toma Monika Wielanek Marzena Szemraj Janusz Nieborowska-Skorska Malgorzata Kolasa Maciej Skorski Tomasz Wysokińska Halina Śliwiński Tomasz |
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Affiliation: | 1.Department of Biology and Pharmaceutical Botany, Medical University of Łódź, Muszyńskiego 1, 90-151, Łódź, Poland ;2.Department of Molecular Genetics, University of Łódź, Pomorska 141/143, 90-236, Łódź, Poland ;3.Department of Plant Physiology and Biochemistry, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237, Łódź, Poland ;4.Department of Medical Biochemistry, Medical University of Łódź, Mazowiecka 6/8, 92-215, Łódź, Poland ;5.Department of Microbiology and Immunology, and Fels Institute for Cancer Research, Temple University, School of Medicine, Philadelphia, PA, USA ;6.Department of Neurosurgery, Medical University, Copernicus Memorial Hospital, Łódź, Poland ; |
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Abstract: | Tumor Biology - Leonurus sibiricus L. is a traditional medicinal plant which occurs in southern Siberia, China, Korea, Japan, and Vietnam. The plant shows several pharmacological effects, but the... |
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