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Inhibition of protein methylesterase 1 decreased cancerous phenotypes in endometrial adenocarcinoma cell lines and xenograft tumor models |
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| Authors: | Pusey Michelle Bail Sophie Xu Yan Buiakova Olesia Nestor Mariya Yang Jing-Jing Rice Lyndi M. |
| Affiliation: | 1.Oncoveda, Cancer Signaling and Cell Cycle Team, Medical Diagnostic Laboratories, LLC, 1000 Waterview Drive, Room 345, Hamilton, NJ, 08691, USA ;2.Invivotek, LLC, 16 Black Forest Road, Hamilton, NJ, 08691, USA ;3.Pathology Department, Members of Genesis Biotechnology Group, LLC, Medical Diagnostic Laboratories LLC, 2439 Kuser Road, Hamilton, NJ, 08690, USA ; |
| Abstract: | Tumor Biology - Protein methylesterase 1 (PME-1) promotes cancerous phenotypes through the demethylation and inactivation of protein phosphatase 2A. We previously demonstrated that PME-1... |
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