社区获得性肺炎与急性上呼吸道感染患儿凝血功能比较

目的比较社区获得性肺炎(CAP)与急性上呼吸道感染患儿的凝血功能结果。方法选取我院在2017年1月至2019年8月期间收治的急性上呼吸道感染患儿和社区获得性肺炎患儿各40例,分别设为上感组和CAP组;另选取同期来我院体检的正常儿童40例,设为正常组。收集三组对象的血样标本,检测并比较三组的凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、血浆D-二聚体(DD)、纤维蛋白原(FIB)。结果三组的TT、PT、APTT无统计学差异(P>0.05);CAP组的DD、FIB均显著高于上感组和正常组,上感组的DD、FIB均显著高于正常组,差异有统计学意义(P<0.05)。结论社区获得性肺炎和急性上呼吸道感染患儿在DD和FIB两项凝血指标方面差异显著,可作为早期评估病情严重程度和预后的重要指标,能够增加诊断精度,提高诊断速度,有助于临床对患儿进行早期治疗。

Comparison on the Coagulation Function Between Children with Community-Acquired Pneumonia and Children with Acute Upper Respiratory Infection

Objective To compare the results of coagulation function between children with community-acquired pneumonia(CAP and children with acute upper respiratory infection.Methods 40 children with acute upper respiratory tract infection and 40 children with community-acquired pneumonia treated in our hospital from January 2017 to August 2019 were selected as the acute upper respiratory tract infection group and the CAP group respectively.40 normal children with physical examination at the same period were selected as normal group.Blood samples were collected from three groups,and the thrombin time(TT),prothrombin time(PT),activated partial thromboplastin time(APTT),and plasma D-dimer(DD)and fibrinogen(FIB)were detected and compared among the three groups.Results No statistical difference was found in the TT,PT and APTT among three groups(P>0.05).The DD and FIB of CAP group were significantly higher than those of acute upper respiratory tract infection group and normal group,and the DD and FIB of acute upper respiratory tract infection group were significantly higher than those of normal group(P<0.05).Conclusions DD and FIB as coagulation indicators have significant differences between children with community-acquired pneumonia and children with acute upper respiratory tract infection,which can be used as important indicators to evaluate the severity and prognosis of the disease in the early stage,increase the accuracy of diagnosis,improve the speed of diagnosis,and help the early treatment of children in clinic.