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Resecting a giant malignant lung tumor in a patient with unilateral acute interstitial pneumonitis
Affiliation:1. Department of Thoracic Surgery, Ohta Nishinouchi Hospital, 2-5-20, Nishinouchi, Koriyama, Fukushima, Japan;2. Department of Respiratory Medicine, Ohta Nishinouchi Hospital, 2-5-20, Nishinouchi, Koriyama, Fukushima, Japan;1. Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-0366, USA;2. Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-1068, USA;3. Sealy Center for Structural Biology and Molecular Biophysics, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-1068, USA;4. Isis Clinical Research, LLC, 6836 Austin Center Blvd. Ste 180, Austin, TX 78731, USA;1. Department of Pathology, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada;2. Department of Medicine and Centre for Heart Lung Innovation, University of British Columbia, Vancouver, BC, Canada;1. Department of Urology, St. Marianna University School of Medicine Hospital, Kawasaki, Kanagawa, Japan;2. Division of Nephrology and Hypertension, St. Marianna University School of Medicine Hospital, Kawasaki, Kanagawa, Japan;3. Recipient Renal Transplantation coordinator, St. Marianna University School of Medicine Hospital, Kawasaki, Kanagawa, Japan;1. Division of Nephrology and Endocrinology, The University of Tokyo, Japan;2. Department of Nephrology and Hypertension, St. Marianna University School of Medicine, Miyamae-ku, Kanagawa, Japan;3. Department of Urology, St. Marianna University School of Medicine, Miyamae-ku, Kanagawa, Japan;1. Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan;2. Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan;3. AIDS Medical Center; National Hospital Organization Osaka National Hospital, Fukuoka, Japan;4. Department of Immunology and Infectious Diseases, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan;5. Yokohama Municipal Citizen''s Hospital, Tokyo, Japan;6. AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan;7. Clinical Research Center, National Hospital Organization Nagasaki Medical Center, Tokyo, Japan;8. Department of Gastroenterology and Hepatology, Shizuoka Hospital, University of Juntendo, Tokyo, Japan;9. Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Abstract:
Acute interstitial pneumonia is a rare and fulminant form of idiopathic interstitial lung disease. Here, we report a case of a giant malignant sarcomatoid tumor of the left lung with unilateral lung infiltration. The tumor was resected under venovenous extracorporeal membrane oxygenation support. Right middle lung lobe biopsy revealed alveolar epithelial hyperplasia, mild interstitial fibrosis, and interstitial edema. The patient was diagnosed with acute interstitial pneumonitis, and effectively treated with steroid pulse therapy followed by prednisolone. In this case, the contralateral lung expansion accomplished with tumor resection, definitive diagnosis based on lung biopsy, and corticosteroid treatment possibly improved the outcome.
Keywords:Lung sarcomatoid tumor  Extracorporeal membrane oxygenation  Acute interstitial pneumonia  AIP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0030"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Acute interstitial pneumonitis  ECMO"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Extracorporeal membrane oxygenation  P/F ratio"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Ratio of arterial partial pressure of oxygen to the inspired fraction of oxygen  POD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Postoperative day
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