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Decrease in outpatient department visits and operative interventions due to bisphosphonates in children with osteogenesis imperfecta
Authors:F. de Graaff  W. Verra  J. E. H. Pruijs  R. J. B. Sakkers
Affiliation:(1) Department of Orthopaedic Surgery, Wilhelmina Children’s Hospital (University Medical Center Utrecht), P.O. Box 85090, 3508 AB Utrecht, The Netherlands;
Abstract:

Introduction  

Bisphosphonates are currently the medical treatment most often used in children with osteogenesis imperfecta (OI). The purpose of this retrospective pre–post study was to evaluate the efficacy of treatment with bisphosphonates. We measured the effect by evaluating the number of outpatient department consultations and operative interventions before and after treatment with bisphosphonates in children with OI.
Keywords:Bisphosphonates   Osteogenesis imperfecta   Children   Outpatient department   Operative intervention
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