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Characteristics of BRAFV600E Mutant,Deficient Mismatch Repair/Proficient Mismatch Repair,Metastatic Colorectal Cancer: A Multicenter Series of 287 Patients
Authors:Christelle de la Fouchardière  Romain Cohen  David Malka  Rosine Guimbaud  Héloïse Bourien  Astrid Lièvre  Wulfran Cacheux  Pascal Artru  Eric François  Marine Gilabert  Emmanuelle Samalin-Scalzi  Aziz Zaanan  Vincent Hautefeuille  Benoit Rousseau  Hélène Senellart  Romain Coriat  Ronan Flippot  Françoise Desseigne  Audrey Lardy-Cleaud  David Tougeron
Affiliation:1. Medical Oncology Department, Centre Leon Berard, Lyon I University, Lyon, France;2. Medical Oncology Department, AP-HP, Saint-Antoine Hospital, Sorbonne University, Paris, France;3. Gastrointestinal Oncology Unit, Department of Cancer Medicine, Gustave Roussy, Villejuif, France;4. Department of Medical Oncology, University Hospital Toulouse, Paul Sabatier University, Toulouse, France;5. Department of Medical Oncology, Eugène Marquis Cancer Institute, Rennes, France;6. Gastroenterology Department, Rennes University Hospital, Rennes 1 University, Rennes, France;7. Medical Oncology Department, Institut Curie, René Huguenin Hospital, Saint-Cloud, France;8. Gastrointestinal Oncology, Jean-Mermoz Hospital, Lyon, France;9. Gastroenterology Department, Antoine Lacassagne Cancer Centre, Nice, France;10. Medical Oncology Department, Paoli-Calmettes Institute, Aix-Marseille University, Marseille, France;11. Digestive Oncology Department, Montpellier Cancer Institute, Montpellier, France;12. Department of Gastroenterology and Digestive Oncology, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris Descartes University, Sorbonne Paris Cité, INSERM UMR-S1147, Paris, France;13. Department of Digestive Oncology, Amiens University Hospital, Amiens, France;14. Department of Oncology, Henri Mondor Hospital, AP-HP, Créteil, France;15. René Gauducheau West Cancer Institute, Saint-Herblain, France;16. Gastrointestinal Oncology Unit, CHU Cochin-Port-Royal, Paris, France;17. Clinical Research and Innovation Department, Leon Berard Cancer Centre, Lyon, France;18. Department of Gastroenterology, Poitiers University Hospital, Poitiers, France
Abstract:
Keywords:Colorectal cancer  BRAF  Mismatch repair testing  Prognostic  Decision making
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