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滋阴清热法为主治疗咳嗽变异性哮喘的随机对照研究
引用本文:支艳,杨明会,张印,刘毅,赵宏.滋阴清热法为主治疗咳嗽变异性哮喘的随机对照研究[J].中华中医药学刊,2011(5):1041-1043.
作者姓名:支艳  杨明会  张印  刘毅  赵宏
作者单位:空军总医院中医科;解放军总医院中医研究所;
基金项目:首都医学科技发展基金资助项目(SF-2007-Ⅱ-05)
摘    要:目的:观察滋阴清热法为主治疗咳嗽变异性哮喘(cough variant asthma,CVA)阴虚内热证的有效性及安全性。方法:随机、平行对照临床试验设计,选择符合研究标准的咳嗽变异性哮喘患者70例,治疗组34例、对照组34例(两组各脱落1例)。治疗组给予滋阴清热法为主组方的汤剂,对照组给予茶碱缓释胶囊治疗,100mg,口服,每12h 1次。两组均以4周为1个疗程。分别在治疗前后观察患者咳嗽、咽痒、咯痰、气急等症状变化。结果:治疗4周后,治疗组患者咳嗽、咽痒、咯痰症状明显轻于对照组,两组间差异具有统计学意义(P<0.05)。咳嗽症状疗效比较:治疗组与对照组有效率分别为91.2%和79.4%,两组间差异具有统计学意义(P<0.05)。中医证候综合疗效比较:治疗组与对照组有效率分别为85.3%和70.6%,两组间差异具有统计学意义(P<0.05)。两组在用药期间均未发生不良反应。结论:滋阴清热法为主治疗咳嗽变异性哮喘安全有效。

关 键 词:咳嗽变异性哮喘  滋阴清热法  随机对照试验  中医药疗法

Randomized Controlled Study on Zi Yin Qing Re Therapy for Treatment of Cough Variant Asthma
ZHI Yan,YANG Ming-hui,ZHANG Yin,LIU Yi,ZHAO Hong.Randomized Controlled Study on Zi Yin Qing Re Therapy for Treatment of Cough Variant Asthma[J].Chinese Archives of Traditional Chinese Medicine,2011(5):1041-1043.
Authors:ZHI Yan  YANG Ming-hui  ZHANG Yin  LIU Yi  ZHAO Hong
Institution:ZHI Yan1,YANG Ming-hui2,ZHANG Yin2,LIU Yi2,ZHAO Hong2(1.TCM Department of General Hospital of the Air Force,Beijing 100142,China,2.Institute of TCM,PLA General Hospital,Beijing 100853,China)
Abstract:Objective: To evaluate the efficacy and safety of Zi Yin Qing Re therapy in treating cough variant asthma(CAV) due to yin asthenia and internal heat.Methods: A randomized controlled trial was conducted.70 CVA patients were randomly divided into control group and treatment group,the 34 patients(1 dropped out) in the treatment group were treated with Chinese herbs of Zi Yin Qing Re therapy,and the 34 patients(1 dropped out) in the control group were treated with theophylline sustained-release capsules,100mg,1...
Keywords:cough variant asthma  Zi Yin Qing Re therapy  randomized controlled trial  Traditional Chinese Medicine  
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