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牙髓再生的临床应用与未来
引用本文:刘斌,梁景平. 牙髓再生的临床应用与未来[J]. 中华口腔医学杂志, 2020, 0(1): 50-55
作者姓名:刘斌  梁景平
作者单位:上海交通大学医学院附属第九人民医院牙体牙髓科上海市口腔医学重点实验室上海市口腔医学研究所国家口腔疾病临床研究中心
摘    要:旨在修复牙髓牙本质复合体的牙髓再生治疗是近年来的研究热点,目前仅有牙髓血运重建技术已实现临床初步应用,而干细胞移植和细胞归巢等技术尚处于临床前阶段.经过多年的基础研究和临床实践,牙髓再生特别是牙髓血运重建技术在取得进展的同时也暴露出不少问题,包括概念混淆、适应证选择不当、评价标准不完善等.为此,本综述从牙髓血运重建技术...

关 键 词:干细胞移植  牙髓再生  牙髓血运重建  细胞归巢

Regenerative endodontics:clinical application status and future perspective
Liu Bin,Liang Jingping. Regenerative endodontics:clinical application status and future perspective[J]. Chinese journal of stomatology, 2020, 0(1): 50-55
Authors:Liu Bin  Liang Jingping
Affiliation:(Department of Endodontics and Operative Dentistry,Ninth People′s Hospital,Shanghai Jiao Tong University School of Medicine&Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology&National Clinical Research Center of Stomatology,Shanghai 200011,China)
Abstract:Regenerative endodontic therapy aiming at restoring dentin-pulp complex has been a hot research topic in recent years.Currently,only pulp revascularization has been applied clinically,while stem cell transplantation and cell homing have not been applied in clinical practice.After many years of basic research and clinical practice,regenerative endodontic therapy has made progress.However,it also exposed some problems including confusion of concepts,improper selection of indications,incomplete evaluation criteria.This article summarizes and discusses the current situation,problems and future clinical practice of regenerative endodontic therapy.
Keywords:Stem cell transplantation  Regenerative endodontics  Pulp revascularization  Pulp revitalization  Cell homing
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