High on clopidogrel treatment platelet reactivity is frequent in acute and rare in elective stenting and can be functionally overcome by switch of therapy |
| |
| Authors: | Sarolta Leé ,Katarina Vargová Istvá n Hizoh,Zsó fia Horvá thPetra Gulá csi-Bá rdos,Zsó fia SztupinszkiAnna Apró ,Andrea Ková csIstvá n Pré da,Emese Tó th-Zsá mbokiRó bert G. Kiss |
| |
| Affiliation: | Medical Center, Hungarian Defence Forces, Department of Cardiology, Budapest, Hungary |
| |
| Abstract: | ![]()
The benefit of adjusted antiplatelet therapy in patients with myocardial infarction after primary percutaneous coronary intervention is not well elucidated. We aimed to identify patients with high on treatment platelet reactivity and to gradually adjust antiplatelet therapy. |
| |
| Keywords: | AA, arachidonic-acid ACEI, angiotensin-converting-enzyme inhibitor ACS, acute coronary syndrome ADP, adenosine-diphosphate ARB, angiotensin-II receptor blocker BMI, body mass index CABG, coronary artery bypass graft CAD, coronary artery disease COLL, collagen COX-1, cyclooxygenase-1 CV, coefficient of variation DES, drug eluting stent EPI, epinephrine HPR, high on-clopidogrel treatment platelet reactivity LM, left main coronary artery branch LTA, light transmission aggregometry MACE, major adverse coronary events MI, myocardial infarction NPR, normal platelet reactivity NSTEMI, non ST segment elevation myocardial infarction OR, odds ratio PCI, percutaneous coronary intervention PsNR, clopidogrel pseudo non-responder RNR, clopidogrel real non-responder rpm, rate per minute SA, stable angina STEMI, ST segment elevation myocardial infarction TIMI, thrombolysis in myocardial infarction UAP, unstable angina pectoris |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
