| Abstract: | ![]()
The parotid gland of a 17 year old boy who died from juvenile type of neuronal ceroid-lipofuscinosis contained autofluorescent lipopigments in epithelial and mesenchymal cells that showed the typical curvilinear and fingerprint profiles; these were not mixed with his secretory granules of the epithelial cells. Determination of p-phenylenediamine-mediated peroxidase in this tissue under various conditions yieded normal total enzyme activity and isoenzyme pattern. From these findings it is concluded that the pathological changes in this inherited disease cannot be related to a peroxidase deficiency. |
