儿童神经源性膀胱保守治疗的现状及进展

神经源性膀胱严重危害患儿的生命与生存质量,其治疗是迄今为止尚未解决的难题。由于尿路功能重建手术疗效不确切,目前保守治疗仍是首选的治疗手段。近年来间歇清洁导尿、膀胱功能训练、药物治疗、电刺激及神经调控等技术不断进入临床研究,并显示出良好的应用前景,其中一些方法已成为临床治疗的标准方案。同时组织工程器官与干细胞移植的研究也取得了巨大的进步,为神经源性膀胱的治疗提供了新思路。

Current Status and Progress of Conservative Treatment in Children with Neurogenic Bladder

Neurogenic bladder can seriously endanger the life and life quality of children,the treatment is still an unresolved problem so far. At present,due to the uncertain efficacy of functional urinary tract reconstruction surgery,conservative treatment is still the preferred treatment. In recent years,intermittent clean catheterization,bladder functional training,drug treatment,electrical stimulation and neuromodulation technique have entered clinical research,and showed good prospects,some of which has become the standard of clinical programs. At the same time,tissue engineering organ and stem cell transplantation research have also made great progress,providing new ideas for the treatment of neurogenic bladder.