Occupational and leisure time physical activity and the risk of breast cancer |
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| Affiliation: | 1. Registre Vaudois des Tumeurs, Institut Universitaire de Médecine Sociale et Préventive, Centre Hospitalier Universitaire Vaudois, Falaises 1, CH-1011 Lausanne, Switzerland;2. Istituto di Ricerche Farmacologiche “Mario Negri”, Milano, and Istituto di Statistica Medica e Biometria, Università degli Studi di Milano, Milano, Italy;1. School of Traditional Chinese Medicine, Naval Medical University, Shanghai 200433, China;2. Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, China;1. Université Clermont Auvergne, laboratoire des adaptations métaboliques à l’exercice en conditions physiologiques et pathologiques (AME2P), 63171 Aubière cedex, France;2. INRA, human nutrition unit, UMR1019, 63000 Clermont-Ferrand, France;3. University hospital Clermont-Ferrand, biostatistics unit (DRCI), 63000 Clermont-Ferrand, France;4. Department of human nutrition, 63000 Clermont-Ferrand university hospital, G.-Montpied hospital, Clermont-Ferrand, 63000, France;5. UFR medicine, university Clermont 1, 63000 Clermont-Ferrand, France;6. CRNH-Auvergne, 63000 Clermont-Ferrand, France;7. Department of sport medicine and functional explorations, 63000 Clermont-Ferrand university hospital, G.-Montpied Hospital, Clermont-Ferrand, 63000, France;1. Grupo de Investigación Salud y Movimiento, Universidad Santiago de Cali, Santiago de Cali, Colombia;2. Universidad de San Buenaventura, Santiago de Cali, Colombia;3. Universidad del Valle, Santiago de Cali, Colombia;1. Facultad de Medicina, Clínica Alemana, Universidad del Desarrollo, Santiago, Chile;2. Universidad Internacional Iberoamericana, México;3. Facultad de Ciencias de la Salud, Universidad de Jaén, España;4. Escuela de Kinesiología, Universidad Bernardo O‘Higgins, Santiago, Chile;5. Unidad de Rehabilitación, Instituto Nacional del Cáncer, Santiago, Chile;6. Facultad de Salud, Universidad San Sebastián, Santiago, Chile;7. Servicio de Radioterapia, Instituto Nacional del Cáncer, Santiago, Chile;8. Servicio de Ginecología, Instituto Nacional del Cáncer, Santiago, Chile;1. Service d’oncologie médicale, Hôpital Abderrahmen-Mami, avenue de l’Hôpital, 2080, Ariana, Tunis, Tunisie;2. AROME (Association de radiothérapie oncologie pour la Méditerranée), Paris, France;3. Service de radiothérapie, Institut Salah-Azaïz, Tunis, Tunisie;4. Service de chirurgie carcinologique, Institut Salah-Azaïz, Tunis, Tunisie;5. Service d’anatomie pathologique, Institut Salah-Azaïz, Tunis, Tunisie;6. Service de radiologie, Clinique Pasteur, Tunis, Tunisie;7. AP–HP Tenon, IUC-UPMC, Sorbonne Université, Paris, France;8. AP–HP Henri-Mondor, UPEC, Créteil, France |
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| Abstract: | ![]()
The relationship between occupational and leisure-time activity and the risk of breast cancer was analysed using data from a case–control study conducted in the Swiss Canton of Vaud between 1993 and 1998 on 246 incidents, histologically confirmed breast cancer cases and 374 controls below the age of 75 years, admitted to the same network of hospitals for acute, non neoplastic non hormone-related conditions. For occupational physical activity, the multivariate odds ratios (OR) for the highest versus the lowest level of physical activity were 0.6 (95% confidence interval, CI=0.35–1.04) when aged 15 to 19 years, 0.5 (95% CI=0.26–0.98) when aged 30 to 39 years, and 0.68 (95% CI=0.36–1.28) when aged 50 to 59. For leisure time physical activity, the ORs were 0.4 (95% CI=0.26–0.69), 0.5 (95% CI=0.30–0.81), and 0.4 (95% CI=0.22–0.80) for the highest versus the lowest level, respectively, in the three age groups, and an inverse trend in risk was significant in all groups. This study, based on one of the few European datasets on the issue, further suggests that physical activity is a favourable indicator of breast cancer risk. |
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