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| 丁丙诺啡透皮贴对痔术后镇痛效果的临床研究 | |
| 引用本文： | 崔灿,秦凯健,施兵,干丹,梁榕钰,王云云,娄铁铮,吴炯. 丁丙诺啡透皮贴对痔术后镇痛效果的临床研究[J]. 中华结直肠疾病电子杂志, 2018, 7(1): 32-35. DOI: 10.3877/cma.j.issn.2095-3224.2018.01.007 |
| 作者姓名： | 崔灿 秦凯健 施兵 干丹 梁榕钰 王云云 娄铁铮 吴炯 |
| 作者单位： | 1. 200437 上海中医药大学附属岳阳中西医结合医院肛肠科2. 202153 上海市崇明区第三人民医院普外科 |
| 基金项目： | 上海市卫生和计划生育委员会资助项目(No.201540144) |
| 摘 要： | 目的评价丁丙诺啡透皮贴对痔术后镇痛的临床疗效。 方法将60例行混合痔外剥内扎术患者，随机分为治疗组和对照组，每组各30例。对照组行术后常规治疗，治疗组在常规治疗的基础上加用丁丙诺啡透皮贴。VAS视觉模拟评分比较两组术后镇痛效果及相关不良反应发生情况。 结果两组术后10 h VAS评分差异无统计学意义（Z=-1.240；P=0.215）；术后1天（Z=-3.163；P=0.002），术后2天（Z=-2.793，P=0.005），3天（Z=-3.096，P=0.002）、4天（Z=-2.266，P=0.023）、5天（Z=-2.266，P=0.023）、6天（Z=-2.497，P=0.013）与对照组比较，对照组评分高于治疗组，差异均有统计学意义。两组于术后2天至5天疼痛评分逐渐升高后下降。 结论丁丙诺啡透皮贴对痔术后患者镇痛效果良好，不良反应轻，值得临床推广。 |
| 关 键 词： | 痔 丁丙诺啡透皮贴 痔外剥内扎术 术后镇痛 |
| 收稿时间： | 2017-04-03 |
The clinical study on the analgesic effect of buprenorphine transdermal patch after hemorrhoidectomy |
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| Can Cui,Kaijian Qin,Bing Shi,Dan Gan,Rongyu Liang,Yunyun Wang,Tiezheng Lou,Jiong Wu. The clinical study on the analgesic effect of buprenorphine transdermal patch after hemorrhoidectomy[J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2018, 7(1): 32-35. DOI: 10.3877/cma.j.issn.2095-3224.2018.01.007 | |
| Authors: | Can Cui Kaijian Qin Bing Shi Dan Gan Rongyu Liang Yunyun Wang Tiezheng Lou Jiong Wu |
| Affiliation: | 1. Proctology Department, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China2. Department of General Surgery, The Third People′s Hospital of Chongming, Shanghai202153, China |
| Abstract: | ObjectiveTo evaluate the analgesic effect of buprenorphine transdermal patch after Milligan-Morgan hemorrhoidectomy. MethodsSixty patients under Milligan-Morgan hemorrhoidectomy were randomly divided into 2 groups, each group has 30 cases. The control group received routine postoperative treatment, while the treatment group was treated with buprenorphine transdermal patch on the basis of routine treatment. Compared the analgesic effect and adverse reactions between the two groups. ResultsThere was no significant difference in VAS score between the two groups after operation in 10 h (Z=-1.240; P=0.215). The difference was statistically significant between the two groups after 1 (Z=-3.163; P=0.002), 2 (Z=-2.793, P=0.005), 3 (Z=-3.096, P=0.002)、4 (Z=-2.266, P=0.023)、5 (Z=-2.266, P=0.023)、6 (Z=-2.497, P=0.013) days. From two to five days after surgery, the pain of the two groups gradually increased, and then decreased. ConclusionThe buprenorphine transdermal patches have a good effect on postoperative analgesia of hemorrhoidectomy, and the adverse reactions are mild, so it is worthy of clinic application. |
| Keywords: | Hemorrhoids Buprenorphine transdermal patch Milligan-Morgan hemorrhoidectomy Postoperative analgesia |
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