763例老年住院患者抗菌药物应用分析

目的了解老年住院患者抗菌药物的应用情况。方法回顾性调查2003年1月—2006年12月老年住院病例763份,对使用抗菌药物的种类、应用天数、剂量进行统计比较分析。结果在763例住院患者中,抗菌药物使用率为61.30%,2003年和2004年的抗菌药物使用率约为70.00%,而2005年和2006年的抗菌药物使用率为56.30%和45.70%。单用的患者为81.20%,而联合用药的低于20.00%。大多数抗菌药物的DUI<1,有5种抗菌药物的DUI>1,以第3代头孢菌素类和喹诺酮类抗菌药物为主。结论我中心抗菌药物的应用基本合理,但仍存在个别药物剂量过大,抗菌药物的更换过于频繁。对老年患者使用抗菌药物,要充分考虑老年患者的生理和病理特点。

Analysis of Antibacterial Angents Use in Hospitalized Senile Patients

OBJECTIVE To investigate the use of antibacterial angents of hospitalized senile patients. METHOD With the retrospectively study for 763 senile in-patients from 2003 to 2006 ,the drug types,used days,dosages of antibacterial angents were analyzed statistically. RESULTS About 61.30% in 763 cases were given antibacterial angents,70.00% in 2003 and 2004,56.30% and 45.70% in 2005 and 2006 respectively. 81.20% for single use,less than 20.00% for combined use. DUI of most of antibacterial angents<1.DUI of 5 angents>1,included fluoroquinolones and cephalosporins. CONCLUSION The choice of antibacterial angents for senile in-patients were basically rational.It exists the over-dosage and change frequently for some drugs. The use of antibacterial angents for senile patients,the characteristics of physiology and pathology must be considered carefully.