Polymorphism of HMGA1 is associated with increased risk of type 2 diabetes among Chinese individuals |
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Authors: | L.?Liu,H.?Ding,H.?R.?Wang,Y.?J.?Xu,G.?L.?Cui,P.?H.?Wang,G.?Yuan,X.?F.?Yu mailto:xfyu@.com" title=" xfyu@.com" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,D.?W.?Wang mailto:dwwang@tjh.tjmu.edu.cn" title=" dwwang@tjh.tjmu.edu.cn" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author |
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Affiliation: | (1) Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, 430030 Wuhan, People’s Republic of China; |
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Abstract: |
Aims/hypothesis Variants of the high-mobility group A1 (HMGA1) gene have been shown to be associated with insulin resistance and type 2 diabetes in individuals of European origin. We aimed to determine whether this locus confers significant susceptibility to type 2 diabetes in the Han Chinese population, and thus cross-race susceptibility to type 2 diabetes. |
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