| Etest法和琼脂稀释法检测淋球菌药物敏感性的对比研究 |
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| 引用本文： | 曹文苓,费实,李平,宋卫忠. Etest法和琼脂稀释法检测淋球菌药物敏感性的对比研究[J]. 中国皮肤性病学杂志, 2000, 14(2): 122-123 |
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| 作者姓名： | 曹文苓 费实 李平 宋卫忠 |
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| 作者单位： | 广州市皮肤病防治所,510095 |
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| 摘 要： | 目的 比较Ｅｔｅｓｔ法和琼脂稀释法检测淋球菌对四种抗生素的敏感性。方法 用Ｅｔｅｓｔ法和琼脂稀释法同时测定四种抗生素对淋球菌的最低抑菌浓度。结果 Ｅｔｅｓｔ法和琼脂稀释法测得青霉素，环丙沙星，头孢三嗪，壮观霉素对淋球菌（ＧＣ）的（最低抑菌浓度ＭＩＣ）相关系数分别为０．８７，０．９２，０．９３，０．２２，符合率分别为８２％，８６％，９５％，６５％，Ｅｔｅｓｔ法和琼脂稀释法测得垃观霉素对淋球菌的ＭＩＣ
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| 关 键 词： | 淋球菌 琼脂稀释法 Etest法 药物敏感性 抗生素 |
| 修稿时间： | 1999-03-19 |
Comparison of Etest and Agar Dilution Method in Testing Susceptibility of Neisseria Gonorrhoeae. |
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| Cao Wenling,Fei Shi,Li Ping,et al.. Comparison of Etest and Agar Dilution Method in Testing Susceptibility of Neisseria Gonorrhoeae.[J]. The Chinese Journal of Dermatovenereology, 2000, 14(2): 122-123 |
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| Authors: | Cao Wenling Fei Shi Li Ping et al. |
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| Affiliation: | Cao Wenling,Fei Shi,Li Ping,et al.Dermatosis prevent and cure institute in Guang Zhou,Guang Zhou 510095 |
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| Abstract: | Objective To compare Etest and agar dilution method for testing susceptibilities of Neisseria gonorrhoeae to four antibiotics.Method MICs of four antibotics were determined by Etest and agar dilution method simultaneously.Results MICs obtained by Etest and agar dilution method showed correlation coefficients of 0.87,0.91,0.92,and 0.22,and agreement percentages of 82%,86%,95%,and 65%,for penicillin,ciprofoxacin,ceftriaxone,and spectinomycin,respectively.However,a significant difference (P<0.001) in spectinoomycin,susceptibility was observed between two methods.Conclusion The Etest is an altenmative to agar dilution method for gonococci susceptibility testing to ceftriaxone,penicillin and ciprofloxacin due to its rapid,effectiveness and significant relationship with agar dilution method.It is cautious to test spectionmycin susceptibility by Etest. |
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| Keywords: | Neisseria gonorrhoeae Agar dilution method Etest MIC |
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