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豚鼠离体气管平滑肌舒缩性压力测量法
引用本文:俞晓春 黎曰真 等. 豚鼠离体气管平滑肌舒缩性压力测量法[J]. 江西医学院学报, 2001, 41(1): 13-15
作者姓名:俞晓春 黎曰真 等
作者单位:江西医学院功能中心实验室,江西南昌330006
摘    要:
目的:研究并介绍一种新的离体气管平滑肌舒缩性检测法-压力检测法,方法:采用测压法检测六只完整离体豚鼠气管平滑肌舒缩功能。结果:当注入舒张药异丙肾上腺素时,能记录到舒张曲线,当注入收缩药乙酰胆碱时,能记录到收缩曲线。结论:实验检测证明本方法具有操作简便。灵敏度高,数据准确。曲线清晰,不破坏离体气管结构等优点,是豚鼠离体气管平滑肌功能检测的较佳方法。

关 键 词:气管平滑肌 动物实验 平滑肌功能检测 压力测量法 异丙肾上腺素 乙酰胆碱
文章编号:1000-2294(2001)01-0013-03
修稿时间:2000-09-25

Manometry of Smooth Muscle Isolated from Trachea of Guinea Pig
YU Xiao-chun,LI Yue-zhen,DING Nan-hua,HUANG Xue-shun,WANG Li-wei. Manometry of Smooth Muscle Isolated from Trachea of Guinea Pig[J]. Acta Academiae Medicinae Jiangxi, 2001, 41(1): 13-15
Authors:YU Xiao-chun  LI Yue-zhen  DING Nan-hua  HUANG Xue-shun  WANG Li-wei
Abstract:
Objective:To study and introduce a new manometric method to determine the pressure during contraction and relaxation of isolated smooth muscle from trachea of guinea pig.Material and methods:Isolated specimens of trachea were taken from six guinea pigs and subjected to the physiological recording system (designed by this central laboratory) to be tested respectively.Results:When isoprenaline was injected a relaxation curve could be recorded; while acetylcholine was injected,a contraction curve could be recorded.Conclusion:The results indicate that this method has many advantages,such as easy operation,high sensitivity,exact data,clear curves and withont distruction of tracheal structure and that it is a favorable method for functional determination of isolated tracheal smooth musles of guinea pigs.
Keywords:manometry  trachea  muscle  smooth  muscle contraction  muscle relaxation  animal  experimental  guinea-pig  
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