IGOB131, a novel seed extract of the West African plant <i>Irvingia gabonensis</i>, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation

Authors:	Judith L Ngondi Blanche C Etoundi Christine B Nyangono Carl MF Mbofung Julius E Oben

Affiliation:	(1) Laboratory of Nutrition and Nutritional Biochemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon;(2) Department of Food Science and Nutrition, ENSAI, University of Ngaoundere, BP 686, Ngaoundere, Cameroon

Abstract:	Background A recent in vitro study indicates that IGOB131, a novel seed extract of the traditional West African food plant Irvingia gabonensis, favorably impacts adipogenesis through a variety of critical metabolic pathways including PPAR gamma, leptin, adiponectin, and glycerol-3 phosphate dehydrogenase. This study was therefore aimed at evaluating the effects of IGOB131, an extract of Irvingia gabonensis, on body weight and associated metabolic parameters in overweight human volunteers.

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