| DNEPs在缺血性脊髓损伤手术中的变化及其意义 |
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| 引用本文： | 宋启民,杨卫忠,陈春美,王春华,石松生,贾建文,房新蓉. DNEPs在缺血性脊髓损伤手术中的变化及其意义[J]. 国际神经病学神经外科学杂志, 2009, 36(6) |
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| 作者姓名： | 宋启民 杨卫忠 陈春美 王春华 石松生 贾建文 房新蓉 |
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| 作者单位： | 福建医科大学附属协和医院神经外科研究所,福建,福州,350001;福建医科大学附属协和医院神经外科研究所,福建,福州,350001;福建医科大学附属协和医院神经外科研究所,福建,福州,350001;福建医科大学附属协和医院神经外科研究所,福建,福州,350001;福建医科大学附属协和医院神经外科研究所,福建,福州,350001;福建医科大学附属协和医院神经外科研究所,福建,福州,350001;福建医科大学附属协和医院神经外科研究所,福建,福州,350001 |
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| 基金项目： | 福建省卫生厅青年科研课题 |
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| 摘 要： | 目的观察兔子不同程度缺血性脊髓损伤后经棘突电刺激下传神经源性运动诱发电位(DNEPs)的变化特点,为在脊柱脊髓手术中持续监测脊髓功能提供理论依据。方法通过不同程度的永久性脊髓缺血动物模型,研究经棘突间接电刺激运动诱发电位在缺血早期的变化特点,并分析波形变化与运动功能的相关性。结果经棘突电刺激间接脊髓运动诱发电位对缺血性损伤敏感,血管结扎后30min的波幅与运动功能呈显著性正相关,Pearson相关系数r=0.976,早期波幅变化可以评估预后,波幅与基线的比值与病理损害程度相关。结论经棘突电刺激间接脊髓运动诱发电位可以用于脊柱脊髓手术中连续监测脊髓功能,其对缺血敏感,与运动功能相关,术中应用可以预防术后术后神经功能障碍。
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| 关 键 词： | 术中脊髓监测 下传神经源性运动诱发电位 兔子 |
The change and value of spinous process stimulation motor-evoked potentzals during spinal cord ischemic injury |
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| Song Qi-Min,Yang Wei-Zhong,Chen Chun-Mei,Wang Chun-Hua,Shi Song-Sheng,Jia Jian-Wen,Fang Xin-Rong. The change and value of spinous process stimulation motor-evoked potentzals during spinal cord ischemic injury[J]. Journal of International Neurology and Neurosurgery, 2009, 36(6) |
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| Authors: | Song Qi-Min Yang Wei-Zhong Chen Chun-Mei Wang Chun-Hua Shi Song-Sheng Jia Jian-Wen Fang Xin-Rong |
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| Affiliation: | Song Qi-Min,Yang Wei-Zhong,Chen Chun-Mei,Wang Chun-Hua,Shi Song-Sheng,Jia Jian-Wen,Fang Xin-Rong.Department of Neurosurgery,Union Hospital,Fujian Medical University,Fujian Institute of Neurosurgery,Fuzhou 350001,Fujian Province,China |
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| Abstract: | Objective The spinous process stimulation Descending Neurogenic Evoked Potentials(DNEPs)were monitored in a rabbit model of different levels of spinal cord ischemia to evaluate their accuracy and relationship to clinical status.The value of DNEPs monitoring during surgery is also observed.Methods A modified rabbit spinal cord ischemia model of different levels of permanent spinal cord ischemia was employed(23 rabbits),after baseline DNEPs were obtained,evoked potentials were recorded continuously during and... |
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| Keywords: | intraoperative spinal cord monitoring desending neurogenic evoked potentials rabbits |
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