BiPAP无创通气治疗AECOPD合并Ⅱ型呼吸衰竭的临床研究 |
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引用本文: | 刘文广,李勇,刘飞宇,洪彦科,喻廷凤,陈斌,何正兵,彭光耀.BiPAP无创通气治疗AECOPD合并Ⅱ型呼吸衰竭的临床研究[J].中国现代医生,2012,50(4):79-80,83. |
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作者姓名: | 刘文广 李勇 刘飞宇 洪彦科 喻廷凤 陈斌 何正兵 彭光耀 |
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作者单位: | 湖南省益阳市中心医院呼吸科,湖南益阳,413000 |
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摘 要: | 目的研究在慢性阻塞性肺疾病急性加重期(AECOPD)合并Ⅱ型呼吸衰竭患者中使用BiPAP无创通气的疗效。方法46例AECOPD合并Ⅱ型呼吸衰竭患者分为治疗组23例(常规治疗联合BiPAP无创通气)和对照组23例(常规治疗)。观察治疗前和治疗后1h、4h、24h、48h动脉血气分析与有创通气率、病死率及住院日。结果治疗组相比对照组PaO2上升和PaCO2下降更明显,且治疗组在有创通气率、病死率及住院日等方面均低于对照组。结论BiPAP无创通气治疗AECOPD合并Ⅱ型呼吸衰竭较常规治疗方法能更快、更好地改善患者病情,且可以减少有创通气率、病死率和住院日。
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关 键 词: | 无创通气 慢性阻塞性肺疾病 呼吸衰竭 |
Clinical study of non-invasive bi-level positive pressure ventilation for acute exacerbation of chronic obstructive pulmonary disease patients with Type Ⅱ respiratory failure |
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Authors: | LIU Wenguang LI Yong LIU Feiyu HONG Yanke YU Tingfeng CHEN Bin HE Zhengbing PENG Guangyao |
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Institution: | Respiratory Department of Hunan Province Yiyang Central Hospital,Yiyang 413000,China |
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Abstract: | Objective To study the effect of non-invasive bi-level positive pressure ventilation for acute exacerbation of chronic obstructive pulmonary disease patients with type Ⅱ respiratory failure.Methods A total of 46 AECOPD patients with type Ⅱ respiratory failure were divided into two groups.Treatment group included 23 patients were given routine therapy and non-invasive bi-level positive pressure ventilation;Control group included 23 patients were only given routine therapy.Observations of the clinical indicators of the arterial blood gas analysis,invasive ventilation rate,mortality and hospitalization days were made before and after the treatment at 1 h,4 h,24 h,48 h.Results PaO2 increased and PaCO2 decreased more significantly in treatment group comparing to the control group,and invasive ventilation,the rate of mortality and hospitalization were all lower in the treatment group than in the control group.Conclusion Non-invasive bi-level positive pressure ventilation in the treatment of AECOPD patients with type Ⅱ respiratory failure is better than that of the conventional treatment method,and can be faster,better for improving the patient’s condition,and can reduce invasive ventilation rate,mortality rate and hospital stay. |
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Keywords: | Non-invasive ventilation Chronic obstructive pulmonary disease Respiratory failure |
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