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Repetition of Helicobacter cinaedi infections during chemotherapy for malignant lymphoma
Authors:Ono Masayoshi  Ohnishi Shunsuke  Onishi Reizo  Takahashi Shojiro  Kobayashi Yoshimitsu  Suzuki Mio  Kubo Kimitoshi  Dazai Masayoshi  Yamamoto Junji  Oda Hisashi  Tada Kenji  Takahashi Tatsuro  Miyagishima Takuto
Affiliation:Department of Internal Medicine, Kushiro Rosai Hospital, Japan.
Abstract:
A 70-year-old male, who had undergone resection of gastric malignant lymphoma in 1992, presented with cervical lymph node swelling in January 2008. Pathological examination of the lymph node biopsy demonstrated recurrence of malignant lymphoma, and he was treated with the R-CHOP regimen. Although he did not develop fever during the first through third course of R-CHOP, from the fourth course, he repeatedly demonstrated fever over 38°C for about one week after each course of chemotherapy, despite the absence of neutropenia. Helicobacter cinaedi infection was confirmed by blood culture each time. Although it is difficult to diagnose Helicobacter cinaedi infection by the standard culture method, increased numbers of recent reports especially in immunocompromised patients have emphasized the importance of diagnosing Helicobacter cinaedi infection.
Keywords:
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