Antiarrhythmic effect of heat adaptation in ischemic and reperfusion injury to the heart |
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Authors: | E. A. Monastyrskaya L. M. Belkina E. B. Manukhina I. Yu. Malyshev |
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Affiliation: | (1) Moscow State Medical Stomatology University, Moscow;(2) Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow |
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Abstract: | Study on a model of 6-day dosed adaptation to heat in rats showed that this adaptation decreased the severity of cardiac arrhythmias during ischemic and reperfusion injury. The duration of arrhythmias decreased not only in the ischemic period, but also under conditions of reperfusion. Adaptation delayed the development of arrhythmias during ischemia, decreased the number of animals with late reperfusion arrhythmias, and improved recovery of the heart after ischemia and reperfusion. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 1, pp. 13–16, January, 2007 |
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Keywords: | heat adaptation heart ischemia reperfusion arrhythmias |
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