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Antiarrhythmic effect of heat adaptation in ischemic and reperfusion injury to the heart
Authors:E. A. Monastyrskaya  L. M. Belkina  E. B. Manukhina  I. Yu. Malyshev
Affiliation:(1) Moscow State Medical Stomatology University, Moscow;(2) Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow
Abstract:
Study on a model of 6-day dosed adaptation to heat in rats showed that this adaptation decreased the severity of cardiac arrhythmias during ischemic and reperfusion injury. The duration of arrhythmias decreased not only in the ischemic period, but also under conditions of reperfusion. Adaptation delayed the development of arrhythmias during ischemia, decreased the number of animals with late reperfusion arrhythmias, and improved recovery of the heart after ischemia and reperfusion. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 1, pp. 13–16, January, 2007
Keywords:heat adaptation  heart  ischemia  reperfusion  arrhythmias
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