| 重组人粒细胞集落刺激因子治疗肺癌化疗引起的白细胞减少症 |
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| 引用本文： | 周静. 重组人粒细胞集落刺激因子治疗肺癌化疗引起的白细胞减少症[J]. 现代医院, 2012, 12(9): 22-23 |
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| 作者姓名： | 周静 |
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| 作者单位： | 南通市肿瘤医院,江苏南通,226361 |
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| 摘 要： | 目的了解重组人粒细胞集落刺激因子对肺癌患者化疗引起的白细胞减少症的疗效。方法采用随机分组、自身交叉对比的方法将60例的VIP方案化疗的肺癌患者分为治疗组和对照组,分别以重组人粒细胞集落刺激因子及地榆升白片为升白药物,化疗前及化疗开始后每日检查血常规,白细胞<3.9×109/L开始使用,白细胞>4×109/L停用,分别计算用药天数。结果治疗组白细胞恢复正常的时间少于对照组。结论重组人粒细胞集落刺激因子治疗化疗引起的白细胞减少效果确切,副作用少。
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| 关 键 词： | 重组人粒细胞集落刺激因子 肺癌 化疗 白细胞减少症 |
THE EFFECT OF RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR ON CHEMOTHERAPY-INDUCED LEUKOPENIA IN LUNG CANCER PATIENTS |
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| ZHOU Jing. THE EFFECT OF RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR ON CHEMOTHERAPY-INDUCED LEUKOPENIA IN LUNG CANCER PATIENTS[J]. Modern Hospital, 2012, 12(9): 22-23 |
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| Authors: | ZHOU Jing |
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| Affiliation: | ZHOU Jing Tumor Hospital of Nantong City,Jiangsu Province 226361 PRC |
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| Abstract: | Objective To evaluate the effect of recombinant human granulocyte colony-stimulating factor(rhG-CSF) on chemotherapy-induced leukopenia in lung cancer patients. Methods 60 cases suffering from lung cancer were randomly divided in two groups.One used rhG-CSF,the other used Diyushengbai when WBC<3.9×109/L.Check blood routine everyday until WBC>4×109/L. Results The time of WBC reach normal level in rhG-CSF group was less then in Diyushengbai group(p<0.01). Conclusion rhG-CSF showed high overall response rate to chemotherapy-induced leukopenia reaction with only a few adverse reaction. |
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| Keywords: | rhG-CSF Lung cancer Chemotherapy Leukopenia |
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