老年糖尿病患者血管并发症相关危险因素分析

目的探讨影响老年糖尿病患者血管并发症发生情况的危险因素。方法选择2010年4月-2011年10月间,我院收治的糖尿病患者320名,分别按彩色多普勒超声和眼底血管检查分为大血管病变组（MA）和微血管病变组（MV）及MA＋MV组,比较它们与无血管并发症的老年糖尿病患者在以下指标上的异同：性别、空腹血糖水平（FPG）、糖化血红蛋白（HbA1C）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、总胆固醇（TC）、血清甘油三脂（TG）、病程、血压、体质量指数、吸烟与否。结果 MA组、MV组、MA＋MV组的FPG、HbA1C、LDL、TC、TG、病程、血压、吸烟人数显著高于无血管并发症组,HDL则显著低于无血管并发症组（P〈0.05）;而3组间的差异则并无显著性（P〉0.05）。相关性分析发现,MA与MV存在相关性（χ2=6.3,P〈0.05）。结论临床医生应了解以上血管并发症的危险因素,积极防治血管并发症的发生;当患者出现MA或MV其中之一时,应积极全面检查预防其它血管并发症的发生。

Study on risk factors of vascular complication in elderly patients with diabetes

【Objective】To explore the risk factors of vascular complication in elderly patients with diabetes.【Methods】320 diabetics were divided into three groups as MA,MV,and MA＋MV by COFI and retinal vascular check.Compared some indexes with elderly diabetics without vascular complication.【Resluts】 Indexes of diabetics in these three groups,such as FPG、HbA1C、LDL、TC、TG,course of disease,blood pressure and smoker were significantly higher than control group.On the contrary,HDL was significantly lower（P0.05）.And differences between three groups have no significant（P0.05）.There is correlation between MA and MV（χ2=6.3,P0.05）.【Conclusion】The risk factors this study referred should be taken seriously to prevent vascular complication in elderly patients with diabetes.