子宫动脉舒张早期切迹对妊娠期高血压疾病的预测价值

目的探讨妊娠20～24周孕妇子宫动脉舒张早期切迹与妊娠期高血压病的相关性。方法选取969例妊娠20～24周正常单胎孕妇,应用彩色多普勒超声分别检测孕妇双侧子宫动脉频谱,依据子宫动脉频谱舒张早期有无切迹将随访至产后的798例孕妇分为有切迹组（81例）和无切迹组（717例）。测量计算双侧子宫动脉舒张早期切迹指数（NI）平均值并依据NI平均值分级将798例孕妇分为4组。比较有切迹组与无切迹组以及有切迹组与NI平均值各分级组妊娠期高血压病的发生率。结果 （1）有切迹组（81例）孕妇妊娠期高血压病发生率（21/81,25.9%）比无切迹组（717例）明显增加（35/717,4.9%）,差异有统计学意义（χ2=49.396,P=0.000）。（2）有切迹组（81例）孕妇妊娠期高血压病发生率（21例,25.9%）明显高于NI1级组（36/719,5.0%）,差异有统计学意义（χ2=48.142,P=0.000）;高于NI2级组（6/44,13.6%）,差异无统计学意义（χ2=2.543,P=0.111）;低于NI3级组（8/27,29.6%）,差异无统计学意义（χ2=0.141,P=0.707）;明显低于NI4级组（6/8,75.0%）,差异有统计学意义（χ2=8.297,P=0.004）。结论子宫动脉NI平均值分级方法能够较好地评估妊娠期高血压病。

The value of early diastolic notch of uterine artery in predicting hypertensive disorders in pregnancy

Objective To investigate the relationship between early diastolic notch of uterine artery and hypertensive disorders in pregnancy at 20-24 weeks of gestation.Methods Color Doppler ultrasound was used to detect the spectrum of bilateral uterine artery in 969 pregnant women at 20-24 weeks of gestation.According to whether the notch of uterine artery was present or not,798 pregnant women followeed up till childbirth were divided into two groups：notch group（81 cases） and non-notch group（717 cases）.The average of notch index（NI） of bilateral uterine arteries was calculated.Then bases on the level of NI,798 pregnant women were classified into four groups.The incidence of hypertensive disorders in pregnancy was compared among these groups.Results（1）The incidence（21/81,25.9%）of hypertensive disorders in pregnancy in notch group was significantly higher than that in non-notch group（35/717,4.9%）（χ2 =49.396,P=0.000）.（2）The incidence of hypertensive disorders in pregnancy in notch group（21/81,25.9%） was higher than that in NI 1（36/719,5.0%;χ2=48.142,P=0.000） and NI 2 group（6/44,13.6%;χ2=2.543,P=0.111）,while was lower than NI 3（8/27,29.6%;χ2=0.141,P=0.707） and NI 4 group（6/8,75.0%;χ2=8.297,P=0.004）.Conclusion The method of uterine artery NI classification can well predict the incidence of hypertensive disorders in pregnancy.