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| 火焰原子吸收法测定维生素B12片中钴的含量 | |
| 引用本文： | 毕雪艳. 火焰原子吸收法测定维生素B12片中钴的含量[J]. 药物分析杂志, 2012, 0(5): 904-905 |
| 作者姓名： | 毕雪艳 |
| 作者单位： | 河北省邯郸市药品不良反应和药物滥用监测中心 |
| 摘 要： | 目的:建立火焰原子吸收法测定维生素B12片中钴的含量。方法:检测波长为240.7 nm,灯电流为4.0 mA,狭缝宽度为0.2 nm,燃气流量为2.0 L·min-1,助燃气流量为13.5 L·min-1。结果:钴浓度在0.01～0.20 mg·L-1范围内线性关系良好(r=0.9999),平均加样回收率为98.8%(n=9)。结论:该方法简单,结果准确,灵敏度高,可有效控制维生素B12片的质量。 |
| 关 键 词： | 维生素B12片 钴 含量测定 火焰原子吸收法 质量控制 |
Determination of cobalt in vitamin B12 tablets by flame atomic absorption spectrometry |
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| BI Xue-yan. Determination of cobalt in vitamin B12 tablets by flame atomic absorption spectrometry[J]. Chinese Journal of Pharmaceutical Analysis, 2012, 0(5): 904-905 | |
| Authors: | BI Xue-yan |
| Affiliation: | BI Xue-yan(Center for ADR Monitoring of Handan,Handan 056001,China) |
| Abstract: | Objective:To establish a flame atomic absorption spectrometry method for determination of cobalt in vitamin B12 tablets.Methods: The determined wavelength was at 240.7 nm,the electric current of the light was 4.0 mA,the slit-width was 0.2 nm,the flow rate of burning gas was 2.0 L·min-1,and the flow rate of gas to help burn was 13.5 L·min-1.Results: There was good linear relationship in the range of 0.01-0.20 mg·L-1 with a regression coefficient of 0.9999,and the average recovery was 98.8%(n=9).Conclusion: The method is simple,accurate,sensitive,and can be good used for controlling the of vitamin B12 tablets. |
| Keywords: | vitamin B12 tablets cobalt assay flame atomic absorption spectrometry quality control |
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