近视眼中央角膜厚度和最薄角膜厚度的关系

目的 研究近视患者中央角膜厚度和最薄角膜厚度的大小、位置关系,以及近视程度对角膜厚度的影响.方法 回顾性病例对照研究.以接受近视性屈光手术的150例(300眼)为研究对象,根据等效球镜分为低、中、高近视3组,提取他们的术前Pentacam检查资料.左右眼参数的相关性和差异分别采用Pearson相关分析和配对t检验,多组比较采用方差分析,同一侧眼不同参数差异采用独立样本t检验.结果 左眼平均中央角膜厚度和最薄角膜厚度分别为(555.83±31.83)μm和(552.88±31.48)μm,右眼平均中央角膜厚度和最薄角膜厚度分别为(554.10±31.47) μm和(549.26±31.25)μm.左眼角膜最薄点72.00％(108/150)位于颞下方;右眼角膜最薄点70.67％(106/150)位于颞下方.不同程度近视组间的角膜厚度差异无统计学意义.结论 最薄角膜厚度与中央角膜厚度并不一致,双眼角膜最薄点均主要位于颞下方,其次在鼻下方.角膜厚度与近视程度无关.

The relationship between central corneal thickness and the thinnest corneal thickness in myopic subjects

Objective To investigate the relationship of magnitude and location between central corneal thickness (CCT) and the thinnest corneal thickness (TCT),and the effect of myopia on corneal thickness.Methods Data obtained with a Pentacam from 300 eyes of 150 patients who had undergone refractive surgery for myopia were randomly divided into 3 groups for a retrospective case control study.The relationship and difference in ocular parameters between the fellow eyes were analyzed by Pearson correlations and paired t tests,respectively.Analysis of variance (ANOVA) was used to compare the data among the multiple groups,and an independent samples t test was used to compare data from the ipsilateral eyes.Results The mean CCT was 555.83±31.83 μm and the mean TCT was 552.88±31.4 μm in the left eyes.The mean CCT was 554.10±31.47 μm and the mean TCT was 549.26±31.25 μm in the right eyes.The TCT location was inferotemporal to the corneal apex in 108/150(72.00％) of the left eyes and in 106/150(70.67％) of the right eyes.There were no significant differences in corneal thickness among the three myopic groups.Conclusion TCT was not consist with the CCT.The TCT location was mainly inferotemporal to the corneal apex in both eyes.Corneal thickness has no significant effect on myopia.