3%高渗盐水滴鼻治疗毛细支气管炎婴儿鼻塞的疗效观察

目的：探讨3%高渗盐水滴鼻治疗毛细支气管炎婴儿鼻塞的临床疗效。方法：将108例诊断为毛细支气管炎同时合并鼻塞的婴儿随机分为观察组和对照组各54例。在相同综合治疗的基础上，观察组给予3%高渗盐水滴鼻，每次1滴，每日3次，对照组给予0.9%生理盐水滴鼻，每次1滴，每日3次，直到患儿鼻塞症状消失为止，比较两组患儿鼻塞消失时间、呼吸频率恢复正常时间、吸气三凹征消失时间及治疗后24 h、48 h、72 h睡眠质量评分，并比较两组患儿喂养量下降发生率。结果：观察组与对照组患儿鼻塞消失时间为(3.68±1.58)d、( 4.92±1.99)d，呼吸频率恢复正常时间为(3.86±1.38)d、(4.55±1.42)d，观察组均短于对照组（P均<0.05）；两组患儿吸气三凹征消失时间为（2.96±1.08）d、（3.06±1.10）d，两组比较差异均无统计学意义（P>0.05）；两组患儿治疗后48 h睡眠质量评分为（1.86±0.48）分、（2.25±0.62）分，72 h评分为（0.86±0.43）分、（1.16±0.56）分，观察组优于对照组（P均<0.05）；两组患儿喂养量下降30%以上发生率为35.19%、57.41%，观察组低于对照组（P<0.05）。结论：3%高渗盐水滴鼻治疗毛细支气管炎婴儿鼻塞症状疗效明显，值得临床推广应用。

The Efficacy of 3% Hypertonic Saline Nasal Drip for Infants with Bronchiolitis with Nasal Obstruction

Objective: To investigate the efficacy of 3% hypertonic saline nasal drip in the treatment of infants with bronchiolitis with nasal obstruction. Methods: 108 infants diagnosed as bronchiolitis with nasal obstruction were randomly divided into observation group (54 cases) and control group (54 cases). On the basis of the same comprehensive treatment, the observation group was given 3% hypertonic saline drip nose, 1 drops each time, 3 times a day, and the control group was given 0.9% physiological saline drops nose, 1 drops each time, 3 times a day, until the nasal obstruction disappeared. The time of nasal obstruction disappeared, three depressions sign disappeared, the restorative time of respiration rate and 24h, 48h, 72h sleep quality score were compared between the two groups, and compare the incidence of decreased feeding in two groups of infants. Results: The time of nasal obstruction disappearance in the observation group and the control group was (3.68±1.58) d, (4.92±1.99) d and the recovery time of respiratory frequency was (3.86±1.38) d, (4.55±1.42) d. The differences of the two groups were statistically significant (P <0.05). The time of disappearance of three depressions sign in the two groups was (2.96 ±1.08) d, (3.06±1.10) d and there was no significant difference between the two groups (P>0.05). The score of sleep quality at 48 hours after treatment was (1.86 ±0.48) score, (2.25±0.62) score and the score of 72 hours was (0.86±0.43) score, (1.16±0.56) score, respectively. The observation group was better than the control group (P<0.05). The incidence rate of feeding decreased by more than 30% in the two groups was 35.19% and 57.41%, which was lower in the observation group than that in the control group (P<0.05). Conclusion: 3% hypertonic saline nasal drip is effective in treating infants with bronchiolitis with nasal obstruction. And it is worthy of clinical application.