血清鳞癌相关抗原及糖类抗原对早期宫颈癌的诊断价值

分析血清鳞癌相关抗原及糖类抗原对早期宫颈癌的诊断价值,为临床诊断及治疗提供参考。选取本院2012年12月至2018年6月期间收治的80例早期宫颈癌患者(早期宫颈癌组)的临床资料,分析鳞癌抗原(SCC-Ag)和糖类抗原(CA19-9,CA125,CA153)对早期宫颈癌的诊断价值。以同期健康体检者60例(对照组)和宫颈上皮瘤样病变患者68例(瘤样病变组)为对照。与对照组和瘤样病变组相比,早期宫颈癌组患者血清中SCC-Ag 、CA19-9、CA125、CA153阳性率和水平明显升高(P<0.05),且随着FIGO分期的升高,上述因子水平逐步升高(P<0.05)。因此,血清鳞癌相关抗原联合糖类抗原对早期宫颈癌有重要的诊断价值,值得临床推广。

Diagnostic value of serum squamous cell carcinoma associated antigen and carbohydrate antigen in early cervical cancer

The purpose of this study is to analyze the diagnostic value of serum squamous cell carcinoma associated antigen and carbohydrate antigen in early cervical cancer, so as to provide reference for clinical diagnosis and treatment. The clinical data of 80 early cervical cancer patients (early cervical cancer group) were selected from December 2012 to June 2018 in our hospital to analyze the diagnostic value of SCC-Ag and CA19-9 (CA125, CA153) for early cervical cancer. Patients in the same period of physical examination (control group, n=60) and cervical epithelioid lesion (tumor like lesion group, n=68) were used as controls. Compared with the control group and the tumor like lesion group, the positive rates and levels of SCC-Ag, CA19-9, CA125 and CA153 in the patients with early cervical cancer group were significantly increased (P<0.05), and the level of these factors gradually increased with the increase of FIGO stage (P<0.05). Serum squamous cell carcinoma associated antigen and carbohydrate antigen have important diagnostic value for early cervical cancer, which is worthy of clinical promotion.