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国产麦迪霉素的组分分离和鉴定
引用本文:何华,于如嘏,杨清华,于在东,王晓华,李芸. 国产麦迪霉素的组分分离和鉴定[J]. 中国现代应用药学, 1994, 0(5): 1-3
作者姓名:何华  于如嘏  杨清华  于在东  王晓华  李芸
作者单位:中国药科大学(何华,于如嘏,杨清华),安徽医学科学研究所(于在东,王晓华),杭州市第一人民医院(李芸)
摘    要:
用柱层析法分离得到国产MDM的二个成分,其结构经波谱分析和其它理化性质的分析,证明是SF-837A1和LeucomycinA6,质谱结果表明,它们都含有碳霉氨基糖,碳霉糖和内酯环。

关 键 词:柱层析色谱,大环内酯,麦迪霉素

Isolation and Analysis of Home Made Mam
He Hu,Yu Rugu,Yong Qinghu,Yu Zaidong and Wang Xiaohua. Isolation and Analysis of Home Made Mam[J]. The Chinese Journal of Modern Applied Pharmacy, 1994, 0(5): 1-3
Authors:He Hu  Yu Rugu  Yong Qinghu  Yu Zaidong  Wang Xiaohua
Abstract:
The present paper presents evidence as to the structure of macrolide antibiotics SF-837A1 and LeucomycinA6 which were isolated from home-made MDM by classical column chro-matograph. Mass spectrometry of two macrolides, SF-837A1 and teucomycinA6 revealed thateach is compased of the elements of mycarose, mycaminose and macrocyclic lactone.
Keywords:Midecamycin  Classical Column Chromatography  Macrolide
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