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| 左心室和双心室起搏对心力衰竭患者运动能力影响的荟萃分析 | |
| 引用本文： | 李永乐,万征,芦文丽. 左心室和双心室起搏对心力衰竭患者运动能力影响的荟萃分析[J]. 中华心律失常学杂志, 2009, 13(4): 271-274. DOI: 10.3760/cma.j.issn.1007-6638.2009.04.008 |
| 作者姓名： | 李永乐 万征 芦文丽 |
| 作者单位： | 1. 天津医科大学总医院心内科,300052 2. 天津医科大学公共卫生学院卫生统计学教研室 |
| 摘 要： | 目的比较左心室起搏（LVP）和双心室起搏（BVP）对心力衰竭患者运动能力的影响。方法在MEDLINE、Cochrane临床试验中心登记库、EMBASE和中国期刊网中检索以心力衰竭为研究对象，评价了6min步行距离（6MWD）和／或峰值耗氧量（PVO2）的LVP与BVP对比的研究。结果共检索到87篇文献，其中3项研究符合人选标准，共纳入73例患者。交叉起搏4～8周后，BVP组比LVP组的PVO2明显增加[加权均数差（WMD）=-0．35ml·kg·min^-1，95％可信区间（CI-0．66，-0．05），P=0．02]；6MWD在BVP组有增加的趋势，但差异无统计学意义（WMD=-1．2m，95％CI（-7．98，5．57），P=0．73]。结论BVP对心力衰竭患者运动能力的改善可能优于LVP。 |
| 关 键 词： | 左心室起搏 双心室起搏 心力衰竭 荟萃分析 |
A meta-analysis of the effects of left ventricular versus biventricular pacing on exercise capacity in patients with heart failure |
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| LI Yong-le,WAN Zheng,LU Wen-li. A meta-analysis of the effects of left ventricular versus biventricular pacing on exercise capacity in patients with heart failure[J]. Chinese Journal of Cardiac Arrhythmias, 2009, 13(4): 271-274. DOI: 10.3760/cma.j.issn.1007-6638.2009.04.008 | |
| Authors: | LI Yong-le WAN Zheng LU Wen-li |
| Affiliation: | LI Yong-le, WAN Zheng,LU Wen-li( Department of Cardiology, Tianfin Medical Uni- versity General Hospital, Tianjin Medical University, Tianjin 300052, China) |
| Abstract: | Objective To compare the effects of left ventricular pacing(LVP)versus biventricular pacing(BVP)on exercise capacity in patients with heart failure.Methods MEDLINE,Cochrane Controlled Trials Register,EMBASE and China National Knowledge Infrastructure were searched for all publications relating to comparative studies of left ventricular versus biventricular pacing therapy in heart failure.All studies evaluated 6 minute walk distance(6MWD)and/or peak oxygen consumption(PVO2)as outcomes.Meta-analysis was done using the Cochrane Collaboration's RevMan 5.0.Results of 87 reports identified,3 studies foHowing a total was a increase in 6MWD in patients with BVP,but it did not reach statistical significance[WMD=-1.2 m,95%CI(-7.98,5.57),P=0.73].Conclusion BVP may significantly improve exercise capacity compared to LVP in patients with heart failure. |
| Keywords: | Left ventricular pacing Biventricular pacing Heart failure Meta-analysis |
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